搜索
 >  其他蛋白>FGL1 >Cynomolgus / Rhesus macaque FGL1 Protein, Mouse IgG2a Fc Tag

Cynomolgus / Rhesus macaque FGL1 Protein, Mouse IgG2a Fc Tag

此产品为在研产品。如果您对此产品有兴趣,请直接联系我们。我们会根据您的需求相应地加速我们的研发进程,并为您进行产品预留。

分子别名(Synonym)

FGL1,Hepassocin,HP-041,HFREP-1,LFIRE-1,HFREP1

表达区间及表达系统(Source)

Cynomolgus / Rhesus macaque FGL1, Mouse IgG2a Fc Tag (FG1-C5256) is expressed from human 293 cells (HEK293). It contains AA Leu 23 - Ile 312 (Accession # G7N0K6-1).

Predicted N-terminus: Leu 23

蛋白结构(Molecular Characterization)

Online-Res(Leu 23 - Ile 312) G7N0K6-1

This protein carries a mouse IgG2a Fc tag at the C-terminus.

The protein has a calculated MW of 60.8 kDa.

内毒素(Endotoxin)

制剂(Formulation)

Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.

Contact us for customized product form or formulation.

重构方法(Reconstitution)

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储(Storage)

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

No activity loss was observed after storage at:

  1. 4-8°C for 12 months in lyophilized state;
  2. -70°C for 3 months under sterile conditions after reconstitution.
 

背景(Background)

Fibrinogen-like protein 1(FGL1) is also known as HP-041, Hepassocin, HFREP-1, LFIRE-1. The protective effect of fibrinogen-like protein 1 (FGL1) in liver injury has previously been reported. However, studies have shown that FGL1 may be a predictor of GC patients and a target for GC therapy. Immunocytochemical studies revealed that fgl1 selectively binds to defective spermatozoa in the cauda epididymidis. Northern blot analysis and in situ hybridization demonstrated the high expression of fgl1 in the principal cells of the proximal cauda epididymidis. Immunofluorescence analysis using mouse fibrotic lung tissues suggested that fibrotic regions showed increased expressions of Gtse1 and Fgl1, Gtse1 and Fgl1 are suggested to be novel targets for radiation-induced lung fibrosis.

 

前沿进展

货号/价格

FG1-C5256-100ug / ¥3500

FG1-C5256-1mg / ¥23100

开发建议
文档
联系电话:
400-682-2521(全国)
010-57737274(北京)
021-26136428(上海)
订单邮箱:
order.cn@acrobiosystems.com
技术支持邮箱:
techsupport@acrobiosystems.com

消息提示

请输入您的联系方式,再点击提交!

确定