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Human ALK-7 Protein, His Tag

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分子别名(Synonym)

ALK-7,ACTR-IC,ACVR1C

表达区间及表达系统(Source)

Human ALK-7, His Tag (AL7-H52H5) is expressed from human 293 cells (HEK293). It contains AA Glu 21 - Glu 113 (Accession # Q8NER5-1).

Predicted N-terminus: Glu 21

蛋白结构(Molecular Characterization)

Online-Res(Glu 21 - Glu 113) Q8NER5-1

This protein carries a polyhistidine tag at the C-terminus.

The protein has a calculated MW of 13.9 kDa.

内毒素(Endotoxin)

制剂(Formulation)

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

Contact us for customized product form or formulation.

重构方法(Reconstitution)

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储(Storage)

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

No activity loss was observed after storage at:

  1. 4-8°C for 12 months in lyophilized state;
  2. -70°C for 3 months under sterile conditions after reconstitution.
 

背景(Background)

ALK-7 (Activin receptor-like kinase 7) is also known as Activin receptor type-1C, ACTR-IC, ACVR1C. Serine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B and NODAL. Plays a role in cell differentiation, growth arrest and apoptosis.

 

前沿进展

货号/价格

AL7-H52H5-100ug / ¥3000

AL7-H52H5-1mg / ¥19800

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