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FABP6信息

英文名称:Bile acid binding protein
中文名称:胆汁酸结合蛋白
靶点别称
上市药物数量:3
临床药物数量:0
最高研发阶段:批准上市

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FABP6 分子别名

FABP6,ILBP,ILLBP,Gastrotropin,GT,I-15P,I-BABP,I-BALB,I-BAP

FABP6 分子背景

Fatty acid-binding protein 6 (FABP6), is also known as Intestinal bile acid-binding protein (I-BABP), Ileal lipid-binding protein (ILBP), Intestinal 15 kDa protein (I-15P), Gastrotropin (GT). FABP6 is a cytoplasm protein which belongs to the calycin superfamily and fatty-acid binding protein (FABP) family. Isoform 2 of FABP6 is expressed in colorectal adenocarcinomas and their adjacent normal mucosa (at protein level). Isoform 1 of FABP6 is expressed in the jejunum, ileum, cecum and ascending colon intestine. Ileal protein FABP6 stimulates gastric acid and pepsinogen secretion. FABP6 seems to be able to bind to bile salts and bilirubins. Isoform 2 of FABP6 is essential for the survival of colon cancer cells to bile acid-induced apoptosis.

FABP6 前沿进展

FABP6上市药物信息

英文名称 中文名称 研发代码 研发阶段 公司 最早商品名 最早批准国家 最早适应症 最早批准公司 最早批准日期 适应症 临床试验

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