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 > 【MICA】

MICA信息

英文名称：MHC class I polypeptide-related sequence A
中文名称：
靶点别称：
上市药物数量：0
临床药物数量：3
最高研发阶段：临床一期

MICA产品列表

筛选结果
产品库
物种
标签
属性
标记
货号 物种 产品描述 蛋白结构 纯度 活性
MIA-C52H5
Cynomolgus		 Cynomolgus MICA Protein, His Tag (HPLC verified)
MIA-H5221
Human		 Human MICA Protein, His Tag (MALS verified)
MIA-H5253
Human		 Human MICA Protein, Fc Tag
MIA-H5254
Human		 Human MICA (24-309) Protein, Fc Tag (MALS verified)
MIA-H5255
Human		 Human MICA (24-202) Protein, Mouse IgG2a Fc Tag (MALS verified)
MIA-H5256
Human		 Human MICA (24-202) Protein, Llama IgG2b Fc Tag, low endotoxin (MALS verified)
MIA-H5259
Human		 Human MICA Protein, IgG4 Fc Tag
MIA-H52H7
Human		 Human MICA (24-202) Protein, His Tag (MALS verified)
MIA-H82E4
Human		 Biotinylated Human MICA (201-309) Protein, His,Avitag™ (MALS verified)
MIA-H82E6
Human		 Biotinylated Human MICA Protein, His,Avitag™ (MALS verified)
MIA-H82F6
Human		 Biotinylated Human MICA Protein, Fc,Avitag™ (MALS verified)
MIA-H82Q7
Human		 Biotinylated Human MICA (201-309) Protein, His,Avitag™
ACRO质量管理体系
 
评论(1)
MIA-H5221|Human MICA Protein, His Tag (MALS verified)
  1. 182XXXXXXX6
    2. 1人赞
  2. 购买human MIA 蛋白主要用于相关靶点单克隆抗体筛选及鉴定工作，该产品亲和力高，实验数据稳定性好，性价比远高于同行产品，值得推荐！
  3. >
  4. 2022-09-27
 

MICA分子别名

MIC-A

MICA分子背景

MHC class I polypeptide-related sequence A (MICA) belongs to the MHC class I family and MIC subfamily. MICA contains one Ig-like C1-type (immunoglobulin-like) domain. Unlike classical MHC class I molecules, MICA does not form a heterodimer with beta-2-microglobulin. MICA acts as a stress-induced self-antigen that is recognized by gamma delta T-cells. MICA is ligand for the KLRK1/NKG2D receptor. MICA bind to KLRK1 leads to cell lysis.

MICA临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
CLN-619 CLN-619 临床一期 PDI Therapeutics Inc 实体瘤 详情
FT-536 FT-536 临床一期 Fate Therapeutics Inc 卵巢癌, 实体瘤, 腹部肿瘤, 女性生殖系统癌症, 输卵管癌 详情
DM-919 DM-919; DM919 临床一期 D2M Biotherapeutics Inc 实体瘤, 肿瘤 详情

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