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LRP-5信息

英文名称:Low-density lipoprotein receptor-related protein 5
中文名称:低密度脂蛋白受体相关蛋白5
靶点别称
上市药物数量:0
临床药物数量:1
最高研发阶段:临床一期

LRP-5产品列表

货号 物种 产品描述 蛋白结构 纯度 活性
LR5-H5254
Human
Human LRP-5 Protein, Mouse IgG2a Fc Tag
LR5-H82E6
Human
Biotinylated Human LRP-5 Protein, His,Avitag™
ACRO质量管理体系
 
评论(1)
LR5-H5254|Human LRP-5 Protein, Mouse IgG2a Fc Tag
  1. 188XXXXXXX8
  2. 0人赞
  3. 又又又需要百普赛斯的试剂啦,这次百普赛斯服务又让我产生感慨啦,已经下班好久了询问物品,收到第二天一早发到物品信息的回复,结果第二天一早销售就在群里催促仓库回复物品信息了,真的给人的感觉很好
  4. 2022-11-25
 

LRP-5分子别名

LRP5,LRP-5,LRP-7,LRP7,LR3

LRP-5分子背景

Low-density lipoprotein receptor-related protein 5(LRP-5) is also known as BMND1, EVR1, EVR4, HBM, LR3, LRP7, OPPG, OPTA1, VBCH2, LDL receptor related protein 5 and PCLD4. LRP5 is a transmembrane low-density lipoprotein receptor that shares a similar structure with LRP6. LRP5 acts as a co-receptor with LRP6 and the Frizzled protein family members for transducing signals by Wnt proteins through the canonical Wnt pathway. This protein plays a key role in skeletal homeostasis. Mutations in LRP5 can lead to considerable changes in bone mass. A loss-of-function mutation causes osteoporosis-pseudoglioma (decrease in bone mass), while a gain-of-function mutation causes drastic increases in bone mass.

LRP-5临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
BI-905681 BI-905681 临床一期 Boehringer Ingelheim Ltd 肿瘤 详情

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