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PSMA

PSMA信息

英文名称:Prostate-Specific Membrane Antigen上市药物数量5
中文名称前列腺癌特异性膜抗原临床药物数量111
靶点别称EC:3.4.17.21，GIG27，Glutamate carboxypeptidase II，NAALADase I，FOLH，Cell growth-inhibiting gene 27 protein，PSM，N-acetylated-alpha-linked acidic dipeptidase I，GCPII，Folylpoly-gamma-glutamate carboxypeptidase，Folate hydrolase 1，FOLH1，Pteroylpoly-Gamma-Glutamate Carboxypeptidase，Membrane Glutamate Carboxypeptidase，Glutamate Carboxypeptidase 2，Glutamate Carboxylase II，NAALAD1，FGCP，PSMA，MGCP，Folate Hydrolase (Prostate-Specific Membrane Antigen) 1，N-Acetylated Alpha-Linked Acidic Dipeptidase 1，Prostate Specific Membrane Antigen Variant F，Prostate-Specific Membrane Antigen，EC 3.4.17.21，NAALAdase，GCP2最高研发阶段临床三期
英文名称:Prostate-Specific Membrane Antigen
中文名称前列腺癌特异性膜抗原
靶点别称EC:3.4.17.21，GIG27，Glutamate carboxypeptidase II，NAALADase I，FOLH，Cell growth-inhibiting gene 27 protein，PSM，N-acetylated-alpha-linked acidic dipeptidase I，GCPII，Folylpoly-gamma-glutamate carboxypeptidase，Folate hydrolase 1，FOLH1，Pteroylpoly-Gamma-Glutamate Carboxypeptidase，Membrane Glutamate Carboxypeptidase，Glutamate Carboxypeptidase 2，Glutamate Carboxylase II，NAALAD1，FGCP，PSMA，MGCP，Folate Hydrolase (Prostate-Specific Membrane Antigen) 1，N-Acetylated Alpha-Linked Acidic Dipeptidase 1，Prostate Specific Membrane Antigen Variant F，Prostate-Specific Membrane Antigen，EC 3.4.17.21，NAALAdase，GCP2
上市药物数量5
临床药物数量111
最高研发阶段Phase 3 Clinical

PSMA产品列表

  • 属性

    Protein (13)Beads (1)Antibody (1)Cell (1)Kits (1)

  • 产品库

    在线 (17)

  • 物种

    Human (9)Cynomolgus (2)Mouse (4)Rat (1)Rabbit (1)

  • 标签

    His Tag (6)His Tag & Avi Tag (3)Fc Tag (2)- (4)Fc Tag & Avi Tag (2)

  • 标记

    Unconjugated (7)Biotin-labeled (5)FITC Labeled (1)- (3)PE Labeled (1)

共 17 项数据
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PSMA分子背景

Prostate-specific membrane antigen (PSMA) is also known as Folate hydrolase 1 (FOLH1), Glutamate carboxypeptidase 2 (GCP2), N-acetylated-alpha-linked acidic dipeptidase I (NAALAD1), which belongs to the peptidase M28 family and M28B subfamily. FOLH1 / PSMA is stable at pH greater than 6.5. FOLH1 / PSMA is a type II transmembrane zinc metallopeptidase that is most highly expressed in the nervous system, prostate, kidney, and small intestine. FOLH1 / GCP-2 is homodimer and binds 2 zinc ions per subunit, and required for NAALADase activity. The catalytic activity of PSMA involved in releasing of an unsubstituted, C-terminal glutamyl residue, typically from Ac-Asp-Glu or folylpoly – gamma - glutamates. FOLH1 / GCP-2 / PSMA has both folate hydrolase and N – acetylated – alpha – linked - acidic dipeptidase (NAALADase) activity and has a preference for tri-alpha-glutamate peptides. GCP-2 / PSMA involved in prostate tumor progression and also exhibits a dipeptidyl-peptidase IV type activity. In vitro, cleaves Gly-Pro-AMC.

PSMA分子别名

FOLH1,PSMA,GIG27,FOLH,NAALAD1,PSM,NAALADase I,GCPII,FGCP

产品评论

  • 21********qq.com 2026-04-28
    0人点赞
    Human PSMA / FOLH1 Protein, His Tag (active enzyme, MALS verified)
    这次回购的human PSMA重组蛋白纯度高，SDS-PAGE跑出来的条带清晰单一，完全没有杂带干扰；其次是活性，用它做的ELISA实验OD值稳定，重复性超赞。Western blot结果完美呈现，顺利推进了项目进度。值得选购。
  • 2026-04-13
    0人点赞
    Human PSMA / FOLH1 Protein, His Tag (active enzyme, MALS verified)
    高纯度（>95%），批次稳定性好 、 HEK293表达系统，蛋白折叠和糖基化更接近天然状态 、具有完整的酶活性（active enzyme），适合功能研究 、生物活性经多种方法验证（ELISA、FACS、SEC-MALS） 、内毒素水平低，适合细胞实验 整体来说，PSA-H52H3是一款质量可靠、活性验证充分的科研级重组蛋白
  • 22********qq.com 2026-03-10
    0人点赞
    Human PSMA / FOLH1 Protein, His Tag (active enzyme, MALS verified)
    在双特异性抗体研发过程中用到该货号PSMA重组蛋白，使用该蛋白先后进行了纳米抗体改造及双特异性抗体活性检测试验。无论在抗体筛选，还是抗体ELISA活性检测中，拿到的数据假阳性概率极低。ACRO重组蛋白质量越来越好了，值得信赖。
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