膜杰作
Star Staining
分子别名（Synonym）
FGFR4,CD334,JTK2,MGC20292,TKF
表达区间及表达系统（Source）
Human FGF R4, His Tag (FG4-H5228) is expressed from human 293 cells (HEK293). It contains AA Leu 22 - Asp 369 (Accession # P22455-1).
Predicted N-terminus: Leu 22
Request for sequence
蛋白结构（Molecular Characterization）
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 39.3 kDa. The protein migrates as 50-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
内毒素（Endotoxin）
Less than 1.0 EU per μg by the LAL method.
纯度（Purity）
>95% as determined by SDS-PAGE.
制剂（Formulation）
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
重构方法（Reconstitution）
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存储（Storage）
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
- -20°C to -70°C for 12 months in lyophilized state;
- -70°C for 3 months under sterile conditions after reconstitution.
质量管理控制体系（QMS）
电泳（SDS-PAGE）
Human FGF R4, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.
- 182XXXXXXX4
- This protein has a particularly good affinity and is relatively stable. It is dissolved under recommended conditions, and there is little difference between batches when used. In ELISA experiments, it has good reproducibility whether used as a coating or as a standard substance. protocal is very detailed, there are giveaways, logistics is fast
- 2023-4-12
- 651XXXXXXX
- The c-MET protein was delivered on time and we were able to use this protein for ELISA screening. I was able to get really good results from using this protein and would come back to Acrobiosystems to reorder this protein or order other proteins that I will need for future experiments.
- 2022-6-10
- 188XXXXXXX9
- 此蛋白亲和力特别好，而且比较稳定，在推荐的条件下进行溶解处理，使用时不同批次之间差异很小，在ELISA实验中，不管是用于包被还是标准品都有很好的重现性，后续还会继续使用，而且也会尝试其他蛋白。protocal也很详细，还有赠品，物流也快
- 2023-3-19
产品推荐（Recommended Products）
背景（Background）
Fibroblast growth factor receptor 4(FGFR4) is also known as CD334, JTK2, hydroxyaryl-protein kinase, TKF, protein-tyrosine kinase . The FGFR4 gene provides instructions for making a protein called fibroblast growth factor receptor 4. This protein is part of a family of fibroblast growth factor receptors that share similar structures and functions. These receptor proteins play a role in important processes such as cell division, regulating cell growth and maturation, formation of blood vessels, wound healing, and embryo development.The FGFR4 protein interacts with specific growth factors to conduct signals from the environment outside the cell to the nucleus. The nucleus responds to these signals by switching on or off appropriate genes that help the cell adjust to changes in the environment. In response, the cell might divide, move, or mature to take on specialized functions. Although specific functions of FGFR4 remain unclear, studies indicate that the gene is involved in muscle development and the maturation of bone cells in the skull. The FGFR4 gene may also play a role in the development and maintenance of specialized cells (called foveal cones) in the light-sensitive layer (the retina) at the back of the eye.
