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 > 【CCL19】

CCL19信息

英文名称:C-C motif chemokine 19
中文名称:趋化因子CCL19
靶点别称:Beta-chemokine exodus-3,CK beta-11,Epstein-Barr virus-induced molecule 1 ligand chemokine,EBI1 ligand chemokine,ELC,Macrophage inflammatory protein 3 beta,MIP-3-beta,Small-inducible cytokine A19,MIP3B,SCYA19
上市药物数量:0
临床药物数量:1
最高研发阶段:临床一期

CCL19产品列表

产品库
物种
标签
属性
货号 物种 产品描述 蛋白结构 纯度 活性
CC9-H5215
Human
Human CCL19 / MIP-3 beta Protein, Tag Free (HPLC verified)
ACRO质量管理体系
 
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CCL19 分子别名

CCL19,MIP-3 beta,MIP-3-beta,ELC,MIP3B,SCYA19,EBI1 ligand chemokine

CCL19 分子背景

C-C motif chemokine 19(CCL19) is as known as CK beta-11, ELC, MIP3B and SCYA19. May play a role not only in inflammatory and immunological responses but also in normal lymphocyte recirculation and homing. May play an important role in trafficking of T-cells in thymus, and T-cell and B-cell migration to secondary lymphoid organs. Binds to chemokine receptor CCR7. Recombinant CCL19 shows potent chemotactic activity for T-cells and B-cells but not for granulocytes and monocytes. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.

CCL19 前沿进展

CCL19临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
Anti-GPC3 chimeric antigen receptor T cell therapy (Hunan Zhaotai Yongren Biotech/Guangdong Zhaotai Invivo Biomedicine) 临床一期 湖南昭泰涌仁生物科技有限公司, 广东昭泰体内生物医药科技有限公司 鳞状细胞癌, 肝细胞癌 详情

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