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 > 【DLL4】

DLL4信息

英文名称：Delta-like protein 4
中文名称：δ样蛋白-4
靶点别称：Delta-Like Protein 4，Notch Ligand Delta-2，DLL4，Delta4，Delta-Like 4 (Drosophila)，Delta-Like 4 Homolog (Drosophila)，AOS6，Hdelta2，Notch Ligand DLL4，Delta Like Canonical Notch Ligand 4，Delta 4，Delta Ligand 4，Delta-Like 4 Protein，Drosophila Delta Homolog 4，Delta-Like 4 Homolog
上市药物数量：0
临床药物数量：3
最高研发阶段：临床三期

DLL4产品列表

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货号 物种 产品描述 蛋白结构 纯度 活性
GMP-DL4H23
Human		 GMP Biotinylated Human DLL4 Protein, His,Avitag™
GMP-DL4H28
Human		 GMP Human DLL4 Protein, Fc Tag
DL4-H5255
Human		 Human DLL4 Protein, Fc Tag, premium grade
DL4-H5259
Human		 Human DLL4 Protein, Fc Tag (MALS & SPR verified)
DL4-H82E6
Human		 Biotinylated Human DLL4 Protein, His,Avitag™, premium grade
MBS-C013
Human		 ActiveMax® Human DLL4 μBeads, premium grade (for cells)
CEA-B038
Human		 ClinMax™ Human Soluble Delta Like Protein 4 (DLL4) ELISA Kit, PRO
DL4-H5227
Human		 Human DLL4 Protein, His Tag
RES-A022
Human		 resDetect™ Biotinylated Human DLL4 ELISA Kit (Residue Testing)
RES-A052
Human		 resDetect™ Human Fc Tag DLL4 ELISA KIT (Residue Testing)
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评论(1)
DL4-H5259|Human DLL4 Protein, Fc Tag (MALS & SPR verified)
  1. 906XXXXXXX
    2. 4人赞
  2. This product was extremely useful for our T cell work. The vial it came in was easy to use (sometimes you'd be surprised how obtuse the packaging of a compound can be by certain companies) and has not lead to any issues with our research in many months. The only obstacle we have ever faced with adherent cells was as a result of our flat bottom plates being too old (and thus the coating wore off). So this product was more stable and consistent than the plates we put them on!
  3. 2022-07-24
 

DLL4分子别名

DLL4,Delta4

DLL4分子背景

Delta-like protein 4 (DLL4) is also known as Drosophila Delta homolog 4 (Delta4), which contains one DSL domain and eight EGF-like domains. DLL4 is expressed in vascular endothelium. DLL4 is involved in the Notch signaling pathway as Notch ligand, which can activates NOTCH1 and NOTCH4. DLL4 is involved in angiogenesis and negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. DLL4 can bind to Notch-1 and Notch-4.

DLL4临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
TR-009 NOV-1501; ABL001-ABL Bio; ABL-001-ABL Bio; ES-104; CTX-009; HD-B001A; HDB001A; TR-009 临床三期 Abl Bio Inc 胆管癌, 实体瘤, 直肠癌, 结肠癌, 肿瘤, 胆管上皮癌, 胆道癌, 结直肠癌, 胆囊癌 详情
Navicixizumab OMP-305B83 临床三期 Oncomed Pharmaceuticals Inc 卵巢癌, 实体瘤, 胃癌, 三阴性乳腺癌, 腹膜癌, 结直肠癌, 输卵管癌 详情
Dilpacimab ABT-165; DVD-Ig ABT-165 临床一期 艾伯维 实体瘤, 肿瘤 详情

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