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GM-CSF R alpha信息

英文名称:Granulocyte-macrophage colony-stimulating factor receptor subunit alpha
中文名称:粒细胞-巨噬细胞集落刺激因子受体α亚基
靶点别称:GM-CSF-R-alpha,GMCSFR-alpha,GMR-alpha,CD116,Colony Stimulating Factor 2 Receptor Subunit Alpha,Colony Stimulating Factor 2 Receptor, Alpha, Low-Affinity (Granulocyte-Macrophage),CSF2R,CSF2RAX,CSF2RAY,CSF2RX,CSF2RY,GM-CSF Receptor Alpha Subunit,GMCSFR,GMR,Granulocyte-Macrophage Colony-Stimulating Factor Receptor Alpha Chain,SMDP4,Colony Stimulating Factor 2 Receptor Alpha Subunit,CDw116,CD116 Antigen,Alpha-GM-CSF Receptor,AlphaGMR
上市药物数量:0
临床药物数量:3
最高研发阶段:临床三期

GM-CSF R alpha产品列表

ACRO质量管理体系
 
评论(1)
GRA-H5255|Human GM-CSF R alpha Protein, Fc Tag
  1. 185XXXXXXX0
  2. 0人赞
  3. 该产品用于药物发现高通量筛选, ACRO的GM-CSF与其受体具有很好的亲和力,通过SA捕获0.0625ug/ml GM-CSF,可检测4-60ng/ml GM-CSFR,能够建立稳定的筛选体系,FRET同样具有较高的亲和力。
  4. 2021-09-05
 

GM-CSF R alpha分子别名

GM-CSF R alpha,GM-CSF-R-alpha,GMCSFR-alpha,GMR-alpha,CSF2RA,CSF2R,CSF2RY,CDw116,CD116

GM-CSF R alpha分子背景

GM-CSF R alpha(Granulocyte-macrophage colony-stimulating factor receptor subunit alpha) is also known as CSF2RA, CD116, GMR-alpha. Low affinity receptor for granulocyte-macrophage colony-stimulating factor. Transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells. Hereditary pulmonary alveolar proteinosis (hPAP) is a rare disorder of pulmonary surfactant accumulation and hypoxemic respiratory failure caused by mutations in CSF2RA (encoding the granulocyte/macrophage colony-stimulating factor [GM-CSF] receptor α-chain [CD116]), which results in reduced GM-CSF-dependent pulmonary surfactant clearance by alveolar macrophages.

GM-CSF R alpha临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
Mavrilimumab CAM-3001; KPL-301; GM-CSFR; CAM3001 临床三期 Csl Ltd 巨细胞性动脉炎, 肺炎, 类风湿关节炎, 新型冠状病毒感染 详情
CSF2RA gene-corrected macrophages(University of South Florida) 临床二期 俄罗斯医学科学院 肺泡蛋白沉积症 详情
STSA-1005 STSA-1005; STSA1005 临床一期 舒泰神(北京)生物制药股份有限公司 新型冠状病毒感染 详情

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