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PSCA信息

英文名称:Prostate stem cell antigen
中文名称:前列腺干细胞抗原
靶点别称:Prostate stem cell antigen,UNQ206/PRO232,PSCA,PRO232
上市药物数量:0
临床药物数量:2
最高研发阶段:临床一期

PSCA产品列表

ACRO质量管理体系
 
评论(2)
PSA-H82E3|Biotinylated Human PSCA Protein, His,Avitag™ (MALS verified)
  1. 188XXXXXXX1
  2. 1人赞
  3. 用于流式检测293T细胞过表达的car-psca蛋白表达。抗体生物素偶联,后续可通过荧光标记SA进行流式检测。
  4. 2024-03-22
PSA-M82Ea|Biotinylated Mouse PSCA Protein, His,Avitag™, low endotoxin (MALS verified)
  1. 136XXXXXXX5
  2. 0人赞
  3. 超级好用的蛋白,用来检测做实验结果真的棒棒的,每个月都采购了,我们是忠实的老客户了,希望能一直保证产品的质量,让我们的实验更加成功,省时省力!
  4. 2023-03-13
 

PSCA分子别名

PSCA,UNQ206,PRO232

PSCA分子背景

The Prostate stem cell antigen (PSCA) is a glycosylphosphatidylinositol (GPI)-anchored protein, plays an important role in tumorigenesis. The prostate stem cell antigen (PSCA) gene, which encodes a prostate-specific antigen (PSA), was identified as a gene involved in cell adhesion and proliferation. PSCA may be involved in the regulation of cell proliferation. Has a cell-proliferation inhibition activity in vitro. May act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits nicotine-induced signaling probably implicating alpha-3:beta-2- or alpha-7-containing nAChRs.

PSCA临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
Autologous Anti-PSCA-CAR-4-1BB/TCRzeta-CD19t-expressing T-lymphocytes (City of Hope Medical Center) 临床一期 希望之城国家医疗中心 去势抵抗性前列腺肿瘤, 前列腺癌 详情
124-iodine-labeled PSCA targeting minibody (ImaginAb) 临床一期 加州大学洛杉矶分校 胰腺癌, 膀胱癌, 前列腺癌 详情

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