【前沿进展】ADC药物PK验证，岂能缺少抗MMAE抗体

ACROBiosystems提供可用于MMAE毒理学研究的高质量的鼠源单克隆抗MMAE抗体 (Cat.No. MME-M5252)，可用于对Payload进行PK分析以及偶联定性分析，加速ADC药物的研发进程。

> 高纯度经SDS-PAGE(>95%) & MALS验证(>90%)

The purity of Mouse Anti-MMAE Antibody, Mouse IgG1 (Cat. No. MME-M5252) was more than 90% and the molecular weight of this protein is around 134-163 kDa verified by SEC-MALS.

> 高亲和力经上市抗体药物验证

Immobilized antibody at 1 μg/mL (100 μL/well) can bind Mouse Anti-MMAE Antibody, Mouse IgG1 (Cat. No. MME-M5252) with a linear range of 0.2-2 ng/mL.

> 高特异性

The EC50 value of anti-MMAE antibody to MMAE-conjugated hRS7 (MMAE-ADC) was 0.12 μg/ml. The unconjugated hRS7 antibody was used as a negative control.