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 >  Protein>LIV-1 >LV1-R52H9

Rat LIV-1 / SLC39A6 Protein, His Tag

分子别名(Synonym)

SLC39A6,LIV-1,ZIP6,Zinc transporter ZIP6,ZIP-6

表达区间及表达系统(Source)

Rat LIV-1, His Tag (LV1-R52H9) is expressed from human 293 cells (HEK293). It contains AA Leu 21 - Trp 311 (Accession # Q4V887-1).

Predicted N-terminus: Leu 21

Request for sequence

蛋白结构(Molecular Characterization)

Online(Leu 21 - Trp 311) Q4V887-1

This protein carries a polyhistidine tag at the C-terminus.

The protein has a calculated MW of 34.6 kDa. The protein migrates as 55-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

内毒素(Endotoxin)

Less than 1.0 EU per μg by the LAL method.

纯度(Purity)

>90% as determined by SDS-PAGE.

制剂(Formulation)

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

Contact us for customized product form or formulation.

重构方法(Reconstitution)

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储(Storage)

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

  1. -20°C to -70°C for 12 months in lyophilized state;
  2. -70°C for 3 months under sterile conditions after reconstitution.
 

电泳(SDS-PAGE)

Rat LIV-1, His Tag (Cat. No. LV1-R52H9) SDS-PAGE gel

Rat LIV-1, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90%.

背景(Background)

LIV-1 is also known as SLC39A6, ZIP-6 and Zinc transporter ZIP6. May act as a zinc-influx transporter. Highly expressed in the breast, prostate, placenta, kidney, pituitary and corpus callosum. Weakly expressed in heart and intestine. Also highly expressed in cells derived from an adenocarcinoma of the cervix and lung carcinoma. Up-regulated by estrogen in breast cancer cells lines.

 

 

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LIV-1靶点信息
英文全称:Zinc transporter ZIP6
中文全称:锌转运体ZIP6
种类:Homo sapiens
上市药物数量:0详情
临床药物数量:2详情
最高研发阶段:临床二期
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