膜杰作
Star Staining
分子别名（Synonym）
CDH3,CDHP,Cadherin-3,P-cadherin
表达区间及表达系统（Source）
Human Cadherin-3, His Tag (CA3-H52H3) is expressed from human 293 cells (HEK293). It contains AA Asp 108 - Gly 654 (Accession # P22223-1).
Predicted N-terminus: Asp 108
Request for sequence
蛋白结构（Molecular Characterization）
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 61.9 kDa. The protein migrates as 65-70 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
内毒素（Endotoxin）
Less than 1.0 EU per μg by the LAL method.
纯度（Purity）
>90% as determined by SDS-PAGE.
制剂（Formulation）
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
重构方法（Reconstitution）
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存储（Storage）
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
- -20°C to -70°C for 12 months in lyophilized state;
- -70°C for 3 months under sterile conditions after reconstitution.
电泳（SDS-PAGE）
Human Cadherin-3, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).
背景（Background）
Cadherin-3 （also known as P-cadherin）is a classical cell-to-cell adhesion molecule with a homeostatic function in several normal tissues. In humans, cadherin-3 is only detected in a few organs. However, its overexpression is strongly associated with a poor prognosis in some solid tumors including breast, lung and pancreatic cancers.
