登录 | 注册    关注公众号  
微信公众号
搜索
 >  Antibody>CD28 >CD8-BM225

Biotinylated Anti-Human CD28 Antibody, Mouse IgG1,Avitag™, premium grade

抗体来源(Source)

Biotinylated Anti-Human CD28 Antibody, Mouse IgG1,Avitag, premium grade (CD8-BM225) is recombinantly produced from human 293 cells (HEK293).

It is produced under our rigorous quality control system that incorporates a comprehensive set of tests including sterility and endotoxin tests. Product performance is carefully validated and tested for compatibility for cell culture use or any other applications in the early preclinical stage. When ready to transition into later clinical phases, we also offer a custom GMP protein service that tailors to your needs. We will work with you to customize and develop a GMP-grade product in accordance with your requests that also meets the requirements for raw and ancillary materials use in cell manufacturing of cell-based therapies.

亚型(Isotype)

Mouse IgG1 | Mouse Kappa

偶联(Conjugate)

Biotin

特异性(Specificity)

This product is a specific antibody specifically reacts with CD28.

内毒素(Endotoxin)

Less than 0.002 EU per μg by the LAL method.

纯度(Purity)

>95% as determined by SDS-PAGE.

>95% as determined by SEC-MALS.

无菌(Sterility)

Negative

支原体(Mycoplasma)

Negative.

制剂(Formulation)

Supplied as 0.2 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

Contact us for customized product form or formulation.

运输(Shipping)

This product is supplied and shipped with dry ice, please inquire the shipping cost.

存储(Storage)

For long term storage, the product should be stored at liquid state at -70°C.

This product is stable after storage at:

  1. 2-8°C for 12 months under sterile condition;
  2. -70°C for 24 months.
 

电泳(SDS-PAGE)

CD28 SDS-PAGE

Biotinylated Anti-Human CD28 Antibody, Mouse IgG1,Avitag, premium grade on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.

SEC-MALS

CD28 SEC-MALS

The purity of Biotinylated Anti-Human CD28 Antibody, Mouse IgG1,Avitag, premium grade (Cat. No. CD8-BM225) is more than 95% and the molecular weight of this protein is around 135-165 kDa verified by SEC-MALS.

Report

 

活性(Bioactivity)-ELISA

CD28 ELISA

Immobilized Biotinylated Anti-Human CD28 Antibody, Mouse IgG1,Avitag, premium grade (Cat. No. CD8-BM225) at 1 μg/mL (100 μL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 μg/well) plate can bind Human / Cynomolgus / Rhesus macaque CD28, His Tag with a linear range of 0.2-1 ng/mL (QC tested).

Protocol

 

背景(Background)

T-cell-specific surface glycoprotein CD28 is also known as TP44, is a single-pass type I membrane protein which contains one Ig-like V-type (immunoglobulin-like) domain. is one of the molecules expressed on T cells that provide co-stimulatory signals, which are required for T cell activation. CD28 is the receptor for CD80 (B7.1) and CD86 (B7.2). When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting cells is constitutive. CD28 is the only B7 receptor constitutively expressed on naive T cells.

 

前沿进展

 
 
货号/价格
文档
联系电话:
+86 400-682-2521(全国)
010-53681107(北京)
021-50850665(上海)
运输方式
订单邮箱:
order.cn@acrobiosystems.com
技术支持邮箱:
tech.cn@acrobiosystems.com
CD28靶点信息
英文全称:T-cell-specific surface glycoprotein CD28
中文全称:T细胞特异性表面糖蛋白CD28
种类:Homo sapiens
上市药物数量:0详情
临床药物数量:25详情
最高研发阶段:临床三期
查看更多信息
前沿进展
点击查看详细

消息提示

请输入您的联系方式,再点击提交!

确定