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 >  Protein>ALPP >ALP-C52H3

Cynomolgus ALPP Protein, His Tag

分子别名(Synonym)

PLAP

表达区间及表达系统(Source)

Cynomolgus ALPP, His Tag (ALP-C52H3) is expressed from human 293 cells (HEK293). It contains AA Ile 21 - Asp 504 (Accession # XP_045223825.1).

Predicted N-terminus: Ile 21

Request for sequence

蛋白结构(Molecular Characterization)

ALPP Structure

This protein carries a polyhistidine tag at the C-terminus.

The protein has a calculated MW of 54.6 kDa. The protein migrates as 65-70 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

内毒素(Endotoxin)

Less than 1.0 EU per μg by the LAL method.

纯度(Purity)

>95% as determined by SDS-PAGE.

制剂(Formulation)

Supplied as 0.2 μm filtered solution in 50mM Tris,150mM NaCl pH7.3 with trehalose as protectant.

Contact us for customized product form or formulation.

运输(Shipping)

This product is supplied and shipped with dry ice, please inquire the shipping cost.

存储(Storage)

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

  1. -20°C to -70°C for 12 months in lyophilized state;
  2. -70°C for 3 months under sterile conditions after reconstitution.
 

电泳(SDS-PAGE)

ALPP SDS-PAGE

Cynomolgus ALPP, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95% (With Star Ribbon Pre-stained Protein Marker).

 

背景(Background)

In most mammals there are four different isozymes: placental (ALPP), germ cell (ALPG), intestinal (ALPI) and tissue non-specific (liver/bone/kidney) (ALPL/TP). ALPP is also known as Alkaline phosphatase, placental type and PLAP. Alkaline phosphatase that can hydrolyze various phosphate compounds.

 

前沿进展

 
 
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ALPP靶点信息
英文全称:Alkaline phosphatase, placental type
中文全称:
种类:
上市药物数量:0详情
临床药物数量:1详情
最高研发阶段:临床二期
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