登录 | 注册    关注公众号  
微信公众号
搜索
 >  Antibody>Spike protein >SPN-Y169

Anti-SARS-CoV-2 Spike Antibody, Mouse IgG1 (2C9C9) (XBB.1.5/Omicron Specific)

抗体来源(Source)

Anti-SARS-CoV-2 Spike Antibody, Mouse IgG1 (2C9C9) (XBB.1.5/Omicron Specific) is isolated from a Spike protein infected Mouse and is recombinantly produced from Hybridoma.

克隆号(Clone)

2C9C9

种属(Species)

Mouse

亚型(Isotype)

Mouse IgG1 | Mouse Kappa

偶联(Conjugate)

Unconjugated

抗体类型(Antibody Type)

Hybridoma Monoclonal

种属反应性(Reactivity)

Virus

免疫原(Immunogen)

Recombinant SARS-CoV-2 Spike Trimer Protein (XBB.1.5/Omicron) erived from human 293 cells.

特异性(Specificity)

This product is a specific antibody specifically reacts with SARS-CoV-2 Spike Trimer Protein, His Tag (XBB/Omicron) (MALS verified) (Cat. No. SPN-C5248), SARS-CoV-2 Spike Trimer Protein, His Tag (XBB.1/Omicron) (MALS verified) (Cat. No. SPN-C522t) and SARS-CoV-2 Spike Trimer Protein, His Tag (XBB.1.5/Omicron) (MALS verified) (Cat. No. SPN-C524i). No cross-reactivity is detected with Protein of WT (Cat. No. SPN-C52H9), Alpha (Cat. No. SPN-C52H6), Beta, Gamma (Cat. No. SPN-C52Hg), Delta (Cat. No. SPN-C52He), B.1.1.529/Omicron (Cat. No. SPN-C52Hz), BA.2/Omicron (Cat. No. SPN-C5223), BA.3/Omicron (Cat. No. SPN-C5225), BA.4/Omicron (Cat. No. SPN-C5229), BA.5/Omicron (Cat. No. SPN-C522e), BA.2.12.1/Omicron (Cat. No. SPN-C522d), BQ.1.1/Omicron (Cat. No. SPN-C522s), BA.2.75/Omicron (Cat. No. SPN-C522f), BA.4.6/Omicron (Cat. No. SPN-C522m), BF.7/Omicron (Cat. No. SPN-C522q).

应用(Application)

ApplicationRecommended Usage
ELISA0.8-200 ng/mL

纯度(Purity)

>95% as determined by SDS-PAGE.

纯化(Purification)

Protein A purified/ Protein G purified

制剂(Formulation)

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

Contact us for customized product form or formulation.

重构方法(Reconstitution)

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储(Storage)

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

  1. -20°C to -70°C for 12 months in lyophilized state;
  2. -70°C for 3 months under sterile conditions after reconstitution.
 

电泳(SDS-PAGE)

Spike protein SDS-PAGE

Anti-SARS-CoV-2 Spike Antibody, Mouse IgG1 (2C9C9) (XBB.1.5/Omicron Specific) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95% (With Star Ribbon Pre-stained Protein Marker).

 

活性(Bioactivity)-ELISA

Spike protein ELISA

Immobilized SARS-CoV-2 Spike Trimer Protein, His Tag (XBB/Omicron) (MALS verified) (Cat. No. SPN-C5248), SARS-CoV-2 Spike Trimer Protein, His Tag (XBB.1/Omicron) (MALS verified) (Cat. No. SPN-C522t) and SARS-CoV-2 Spike Trimer Protein, His Tag (XBB.1.5/Omicron) (MALS verified) (Cat. No. SPN-C524i) can bind Anti-SARS-CoV-2 Spike Antibody, Mouse IgG1 (2C9C9) (XBB.1.5/Omicron Specific) (Cat. No. SPN-Y169) with a linear range of 0.391-25 ng/mL (QC tested). The antibody does not bind Spike Protein of WT (Cat. No. SPN-C52H9), Alpha (Cat. No. SPN-C52H6), Beta, Gamma (Cat. No. SPN-C52Hg), Delta (Cat. No. SPN-C52He), B.1.1.529/Omicron (Cat. No. SPN-C52Hz), BA.2/Omicron (Cat. No. SPN-C5223), BA.3/Omicron (Cat. No. SPN-C5225), BA.4/Omicron (Cat. No. SPN-C5229), BA.5/Omicron (Cat. No. SPN-C522e), BA.2.12.1/Omicron (Cat. No. SPN-C522d), BQ.1.1/Omicron (Cat. No. SPN-C522s), BA.2.75/Omicron (Cat. No. SPN-C522f), BA.4.6/Omicron (Cat. No. SPN-C522m), BF.7/Omicron (Cat. No. SPN-C522q) (QC tested).

Protocol

 

背景(Background)

It's been reported that SARS-CoV-2 can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

 

前沿进展

 
 
货号/价格
文档
联系电话:
+86 400-682-2521(全国)
010-53681107(北京)
021-50850665(上海)
运输方式
订单邮箱:
order.cn@acrobiosystems.com
技术支持邮箱:
tech.cn@acrobiosystems.com
Spike protein靶点信息
英文全称:Coronavirus spike glycoprotein
中文全称:冠状病毒刺突糖蛋白
种类:Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) (SARS-CoV-2)
上市药物数量:9详情
临床药物数量:71详情
最高研发阶段:批准上市
查看更多信息
前沿进展
点击查看详细

消息提示

请输入您的联系方式,再点击提交!

确定