描述/背景(Background)
Required to maintain individual mitotic chromosomes dispersed in the cytoplasm following nuclear envelope disassembly . Associates with the surface of the mitotic chromosome, the perichromosomal layer, and covers a substantial fraction of the chromosome surface. Prevents chromosomes from collapsing into a single chromatin mass by forming a steric and electrostatic charge barrier: the protein has a high net electrical charge and acts as a surfactant, dispersing chromosomes and enabling independent chromosome motility.
种属(Host Species)
Rabbit
克隆号(Clone)
7A4
适用方法(Application)
IHC
效价(Property)
1:500
状态(State)
Liquid
阳性对照(Positive Control)
Human Tonsil Tissues
克隆类型(Clonality)
Monoclonal
分子别名(Synonym)
PPP1R105, MIB-1, ki-67
研究领域(Research Field)
Cancer Drug Targets
抗体来源(Source)
Rabbit
同种型(Isotype)
IgG
储存(Storage)
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
典型数据(Typical Data)
质控样本(Control Sample)
Immunohistochemical analysis of paraffin embedded Human tonsil tissue labelled with HGS-S239 at 1/500 dilution.
Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
肿瘤样本(Cancer Sample)
Immunohistochemical analysis of paraffin embedded human cancer tissue labelled with HGS-S239 at 1/500 dilution.
Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.