分子别名(Synonym)
HC14, MCP-2, MCP2, SCYA10, SCYA8
表达区间及表达系统(Source)
Human CCL8 Protein, His Tag (CC8-H5243) is expressed from human 293 cells (HEK293). It contains AA Gln 24 - Pro 99 (Accession # P80075).
Predicted N-terminus: His
蛋白结构(Molecular Characterization)
![CCL8 Structure](/images/structure_Images/CC8-H5243-STC2.jpg)
This protein carries a polyhistidine tag at the N-terminus
The protein has a calculated MW of 10.8 kDa.
制剂(Formulation)
Please contact us for detailed information.
Contact us for customized product form or formulation.
重构方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存储(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
- -20°C to -70°C for 12 months in lyophilized state;
- -70°C for 3 months under sterile conditions after reconstitution.
背景(Background)
This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils. By recruiting leukocytes to sites of inflammation this cytokine may contribute to tumor-associated leukocyte infiltration and to the antiviral state against HIV infection.