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 >  Cell Grade Beads>Her2 >MBS-C006

ActiveMax® Human Her2 μBeads, premium grade (for cells) DMF

热销产品推荐:The Magnetic Stand (Cat.No. MB-01 & Cat.No. MB-02) can be used in conjunction with Beads.
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ProductSizeAmount
ActiveMax® Human Her2 μBeads, premium grade (for cells)2.5 mg2.5 × 10⁷ beads
ActiveMax® Human Her2 μBeads, premium grade (for cells)10 mg (2.5 mg × 4)1.0 × 10⁸ beads

背景(Background)

ActiveMax® Human Her2 μBeads, premium grade (for cells) are produced under sterile manufacturing conditions (ISO 5) , and no animal- or human-derived components are used throughout the production process. It is produced under our rigorous quality control system that includes a comprehensive set of tests including sterility and endotoxin tests.

表达区间及表达系统(Source)

ActiveMax® Human Her2 μBeads, premium grade (for cells) are uniform, superparamagnetic beads of 5.5 µm with streptavidin on its surface and coupled with biotinylated Human Her2 Protein, expressed from human 293 cells (HEK293) and contains AA Thr 23 - Thr 652 (Accession # P04626-1).

应用说明(Application)

ActiveMax® Human Her2 μBeads, premium grade (for cells) are designed to stimulate in vitro Her2-specific CAR-T cells or UCAR-T cells, similar to the tumor cell lines that express human Her2 antigen. It can be used as follows:
Evaluating the characteristics of CAR-T cells or UCAR-T cells.
In vitro expansion of Her2-specific CAR-T cells or UCAR-T cells.
In vitro enrichment of Her2-specific CAR-T cells or UCAR-T cells.

*We also carry ActiveMax® Streptavidin μBeads, premium grade (for cells)(Cat. No. MBS-C009),and it can be used for convenient preparation of your own sterile protein/antibody coupled beads for cell based assay, cell sorting and other applications. The ActiveMax® Streptavidin μBeads, premium grade can also be used together with other ActiveMax® μBeads, premium grade as Isotype control.

重构方法(Reconstitution)

See Certificate of Analysis (CoA) for detailed instruction.

存储(Storage)

This product is stable in storage under the following conditions: -20˚C for 12 months in lyophilized state. -70°C for 3 months under sterile conditions after reconstitution.

Please avoid repeated freeze-thaw cycles after reconstitution. Immediate use after reconstitution is highly recommended.

无菌(Sterility)

Negative

内毒素(Endotoxin)

Less than 0.002 EU per μg by the LAL method.

注意事项(Important Note)

This product is for research use only and not intended for therapeutic or in vivo diagnostic use.

制剂(Formulation)

Please contact us for detailed information.

Contact us for customized product form or formulation.

 

典型数据-Typical Data Please refer to DS document for the assay protocol.

Her2 TYPICAL DATA

Assay of human Her2 protein on the μBeads surface by Flow cytomtry.ActiveMax® Human Her2 μBeads, premium grade (for cells) (Cat. No. MBS-C006) were stained with anti-human Her2 antibody, and then followed by FITC anti-human IgG Fc antibody and analyzed by flow cytometry.

Her2 TYPICAL DATA

Assay of Human Her2 on the μBeads surface by Flow cytometry. ActiveMax® Human Her2 μBeads, premium grade (for cells) (Cat. No. MBS-C006) surface was fluorescently stained using Anti-Her2 antibody and PE-anti-Human IgG Fc, analyzed by flow cytometry (QC tested).

 

前沿进展

 
 
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Her2靶点信息
英文全称:Receptor protein-tyrosine kinase erbB-2
中文全称:受体蛋白酪氨酸激酶 erbB-2
种类:Homo sapiens
上市药物数量:34详情
临床药物数量:202详情
最高研发阶段:批准上市
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