膜杰作
Star Staining
描述/背景（Background）
MET is a tyrosine kinase receptor for the hepatocyte growth factor. It is linked to functions such as cell proliferation, scattering, morphogenesis, and survival. Ligand binding at the cell surface induces autophosphorylation of MET that provides docking sites for downstream signaling molecules. After activation of the ligand, MET interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, and STAT3. There interactions lead to the activation of signaling cascades including RAS-ERK, PI3, kinase-AKT, and PLCgamma-PKC. MET plays a role in embryonic development including gastrulation, development of muscles and neurons, angiogenesis, and kidney formation.
种属（Host Species）
Rabbit
克隆号（Clone）
1A1
适用方法（Application）
IHC
效价（Property）
1：1000
状态（State）
Liquid
阳性对照（Positive Control）
Human Placenta Tissue
克隆类型（Clonality）
Monoclonal
分子别名（Synonym）
C-MET
研究领域（Research Field）
Cancer Drug Targets
抗体来源（Source）
Rabbit
同种型（Isotype）
IgG
储存（Storage）
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
典型数据（Typical Data）
质控样本（Control Sample）
Immunohistochemical analysis of paraffin embedded Human placenta tissue labelled with HGS-S303 at 1/1000 dilution.
Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
肿瘤样本（Cancer Sample）
Immunohistochemical analysis of paraffin embedded human cancer tissue labelled with HGS-S303 at 1/1000 dilution.
Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
