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Human CNR2 Full Length Protein (VLP)

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分子别名(Synonym)

CNR2,cannabinoid receptor 2,CB2,CX5,CB-2,hCB2

表达区间及表达系统(Source)

Human CNR2 Full Length Protein (VLP) (CN2-H52P5) is expressed from human 293 cells (HEK293). It contains AA Met 1 - Cys 360 (Accession # P34972-1).

蛋白结构(Molecular Characterization)

Virus-like particles(VLPs) are formed by self-assembly of envelop/capsid proteins from viruses. Membrane Proteins can be constituted in-situ with VLPs produced from HEK293 cell cultures. These VLPs concentrate conformationally intact membrane proteins directly on the cell surface and produce soluble, high-concentration proteins perfect for immunization and antibody screening.

The VLPs provide the display of properly folded membrane proteins in their native cellular membrane in a compact size of 100~300 nm diameter (similar to the size of most viruses) making it optimal targets for dendritic cells in vivo and surface attachment for phage display.

制剂(Formulation)

Please contact us for detailed information.

Contact us for customized product form or formulation.

运输(Shipping)

This product is supplied and shipped with dry ice, please inquire the shipping cost.

存储(Storage)

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

  1. The product MUST be stored at -70°C or lower upon receipt;
  2. -70°C for 12 months under sterile conditions.
*The isotype control of empty/mock VLP (Cat. No. VLP-N5213) is sold separately and not included in protein, you can follow this link for product information.
 

背景(Background)

CNR2 (also known as cannabinoid receptor type 2, CB2) is a G protein-coupled receptor from the cannabinoid receptor family that in humans is encoded by the CNR2 gene. It is closely related to the cannabinoid receptor type 1 (CB₁), which is largely responsible for the efficacy of endocannabinoid-mediated presynaptic-inhibition, the psychoactive properties of tetrahydrocannabinol (THC), the active agent in cannabis, and other phytocannabinoids (plant cannabinoids). The principal endogenous ligand for the CB₂ receptor is 2-Arachidonoylglycerol (2-AG).

 

前沿进展

 
 
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CNR2靶点信息
英文全称:Cannabinoid CB2 receptor
中文全称:大麻素受体CB2
种类:
上市药物数量:2详情
临床药物数量:15详情
最高研发阶段:批准上市
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