背景(Background)
Claudin18.2 participates in the proliferation, differentiation and migration of tumor cells. Recent studies have identified Claudin18.2 expression as a potential specific marker for the diagnosis and treatment of these tumors. The Claudin18.2 IHC 3B10 Kit is a quick assay to detect Claudin18.2 across tumors to identify patients eligible for multiple targeted therapies. Kit product are manufactured in a dedicated GMP facility and are compliant with our ISO 13485 quality management system.
产品描述(Background)
Analyte | Claudin-18.2 |
Format | 2ml/7.5ml/30ml |
Reactivity | Human |
Species | Mouse |
Regulatory Status | RUO |
Applicable Platform | LEICA BOND III、DAKO link 48 |
组分(Materials Provided)
Recombinant Monoclonal Anti-Claudin18.2 Antibody, Mouse (3B10)
Antibody diluent
应用说明(Application)
The kit is developed for use in the Claudin18.2 protein in the formalin-fixed, paraffin-embedded tissue. It is indicated as an aid in the assessment of Claudin18.2 expression in human tissues.
状态(State)
Liquid
存储(Storage)
Stored at 2°C to 8°C.
质控样本(Control Sample)
Use ACRO Claudin18.2 3B10 kit to stain normal gastric tissue and lung tissue, according to the cross-reactivity experiment, there is no cross-reactive staining result between Claudin-18.2 and Claudin-18.1.
肿瘤样本(Cancer Sample)
一致性(Consistency)
LEICA BOND III and Dako link 48 platform conformance verification, with a high consistency rate (>95%).
Use ACRO Claudin18.2 3B10 kit to stain gastric cancer. The results showed that the staining effect was highly consistent.
扩展性(Extensibility)
ACRO Claudin18.2 3B10 kit expandable test: gastric cancer, pancreatic cancer, colorectal cancer and ovarian Cancer.
Use ACRO Claudin18.2 3B10 kit to stain gastric cancer, pancreatic cancer, colorectal cancer and ovarian cancer tissue samples respectively.
适用性(Applicability)
ACRO Claudin18.2 3B10 kit can be available on the LEICA BOND III and DAKO Link 48 platform.
Use ACRO Claudin18.2 3B10 kit to stain NSCLC tissue samples at Leica BOND-III and Dako link 48.