登录 | 注册    关注公众号  
微信公众号
搜索
 >  Protein>IL-9 >IL9-H5214

Human IL-9 Protein, premium grade

分子别名(Synonym)

Interleukin-9,IL-9,Cytokine P40

表达区间及表达系统(Source)

Human IL-9 Protein, premium grade (IL9-H5214) is expressed from human 293 cells (HEK293). It contains AA Gln 19 - Ile 144 (Accession # P15248-1).

Predicted N-terminus: Gln 19

Human IL-9 Protein, premium grade (IL9-H5214), designed for preclinical stage, has the same activity and performance with GMP Human IL-9 Protein, which enables a seamless transition from preclinical development to clinical phases. Premium Grade product offer a cost efficient alternative of GMP Grade products for the early development phase when safety of raw materials is not top priority. By using Premium Grade products in early development phase, you can transition easily into clinical and commercial phase without need to revalidate the raw materials and modify manufacturing process.

Request for sequence

蛋白结构(Molecular Characterization)

IL-9 Structure

This protein carries no "tag".

The protein has a calculated MW of 14.1 kDa. The protein migrates as 30 kDa±3 kDa under reducing (R) condition, and 30 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.

内毒素(Endotoxin)

Less than 0.01 EU per μg by the LAL method.

宿主蛋白残留(Host Cell Protein)

<0.5 ng/µg of protein tested by ELISA.

宿主核酸残留(Host Cell DNA)

<0.02 ng/μg of protein tested by qPCR.

无菌(Sterility)

Negative

支原体(Mycoplasma)

Negative.

纯度(Purity)

>95% as determined by SDS-PAGE.

>95% as determined by SEC-MALS.

制剂(Formulation)

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

Contact us for customized product form or formulation.

重构方法(Reconstitution)

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储(Storage)

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

  1. -20°C to -70°C for 24 months in lyophilized state;
  2. -70°C for 3 months under sterile conditions after reconstitution.
 

电泳(SDS-PAGE)

IL-9 SDS-PAGE

Human IL-9 Protein, premium grade on SDS-PAGE under reducing (R) and non-reducing (NR) conditions. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95% (With Star Ribbon Pre-stained Protein Marker).

SEC-MALS

IL-9 SEC-MALS

The purity of Human IL-9 Protein, premium grade (Cat. No. IL9-H5214) is more than 95% and the molecular weight of this protein is around 18-25 kDa verified by SEC-MALS.

Report

 

活性(Bioactivity)-ELISA

IL-9 ELISA

Immobilized Human IL-9 Protein, premium grade (Cat. No. IL9-H5214) at 5 μg/mL (100 μL/well) can bind Human IL-9R, Fc Tag (Cat. No. ILR-H5251) with a linear range of 2-78 ng/mL (QC tested).

Protocol

 

背景(Background)

Interleukin-9 (IL-9) is expressed primarily by activated T cells. The growth factor and anti apoptotic activities of IL-9 on multiple transformed cells suggest a potential role for the cytokine in tumourigenesis. IL-9 has also been proposed as a candidate gene for asthma IL-9 is a Th2-derived cyto kine that has been reported to regulate T and B cell function. IL-9was first isolated as a factor capable of sustaining the long-termgrowth of murine T cell clones, but has since been demon strated to have in vitro activities on mast cells, erythroid pro genitors, and B cell Ig expression.

 

前沿进展

 
 
货号/价格
文档
联系电话:
+86 400-682-2521(全国)
010-53681107(北京)
021-50850665(上海)
运输方式
订单邮箱:
order.cn@acrobiosystems.com
技术支持邮箱:
tech.cn@acrobiosystems.com
IL-9靶点信息
英文全称:Interleukin-9
中文全称:白细胞介素-9
种类:Homo sapiens
上市药物数量:0详情
临床药物数量:1详情
最高研发阶段:临床二期
查看更多信息
前沿进展
点击查看详细
相关产品
View All IL-9 View All NA

消息提示

请输入您的联系方式,再点击提交!

确定