膜杰作
Star Staining
抗体来源（Source）
Rabbit
亚型（Isotype）
Rabbit IgG
偶联（Conjugate）
Unconjugated
特异性（Specificity）
This product is a specific antibody specifically reacts with NG2/Cspg4.
纯化（Purification）
Protein A purified/ Protein G purified
制剂（Formulation）
Supplied as 0.2 μm filtered solution in undefined.
Contact us for customized product form or formulation.
运输（Shipping）
This product is supplied and shipped with blue ice, please inquire the shipping cost.
存储（Storage）
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
- Shipped at 4°C. Store at -20/4°C for months and -80°C for years. Avoid freeze/thaw cycle.
活性（Bioactivity）-Immunostaining
Immunofluorescent staining (10X) of cerebral organoid-derived cells (CIPO-BWL001K) labeling NG2 (Red) with purified NG4-S455 at 1:200 dilution. DAPI (blue) was used as nuclear counterstain.
Protocol
背景（Background）
Neuron-glial antigen 2 (NG2), also known as chondroitin sulphate proteoglycan 4 (CSPG4), is a surface type I transmembrane core proteoglycan that is crucially involved in cell survival, migration and angiogenesis. In the central nervous system, NG2/Cspg4 is expressed in certain glia cells which are sometimes called polydendrocytes or oligodendrocyte precursor cells (OPCs), as well as in mesenchymal stem cells, osteoblasts, melanocytes, smooth muscle cells and macrophages. NG2/Cspg4-mediated signaling has been shown to play an important role in the progression of several tumor types including glioblastoma and malignant melanoma. NG2/Cspg4 is also a typical marker for vessel-surrounding pericytes, which contribute to the stabilization of microvessels, the regulation of capillary blood flow and angiogenesis.
