抗体来源(Source)
Rabbit
亚型(Isotype)
Rabbit IgG
偶联(Conjugate)
Unconjugated
特异性(Specificity)
This product is a specific antibody specifically reacts with Olig2.
纯化(Purification)
Protein A purified/ Protein G purified
制剂(Formulation)
Supplied as 0.2 μm filtered solution in undefined.
Contact us for customized product form or formulation.
运输(Shipping)
This product is supplied and shipped with blue ice, please inquire the shipping cost.
存储(Storage)
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
- Shipped at 4°C. Store at -20/4°C for months and -80°C for years. Avoid freeze/thaw cycle.
活性(Bioactivity)-Immunostaining
Immunofluorescent staining (10X) of cerebral organoid-derived cells (CIPO-BWL001K) labeling Olig2 (Red) with purified OL2-S456 at 1:200 dilution. DAPI (blue) was used as nuclear counterstain.
Protocol
背景(Background)
The oligodendrocyte transcription factor 2 (Olig2) is a basic helix-loop-helix transcription factor which is highly expressed in the oligodendrocyte-lineage cells and in oligodendroglial tumors of the brain as well. Olig2 is an essential regulator of ventral neuroectodermal progenitor cell fate, especially regulating key stages of early oligodendrocyte development. Olig2 has also been reported to act as a gene repressor to determine the cell fate of motor neurons in the spinal cord. Olig2 is a useful marker for primary and mature oligodendrocytes as well as a marker of malignant glioma.