分子别名(Synonym)
NA,Neuraminidase
表达区间及表达系统(Source)
Influenza A virus (A/Massachusetts/18/2022) NA(H3N2) Protein, His Tag (NEE-V524v) is expressed from human 293 cells (HEK293). It contains AA Lys 80 - Thr 469 (Accession # EPI2096147, GISAID).
Predicted N-terminus: His
蛋白结构(Molecular Characterization)
![Neuraminidase (NA) Structure](/images/structure_Images/NEE-V524v-STC2.jpg)
This protein carries a polyhistidine tag at the N-terminus.
The protein has a calculated MW of 51.0 kDa.
制剂(Formulation)
Please contact us for detailed information.
Contact us for customized product form or formulation.
重构方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存储(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
- -20°C to -70°C for 12 months in lyophilized state;
- -70°C for 3 months under sterile conditions after reconstitution.
背景(Background)
Influenza, commonly known as 'the flu', is an infectious disease of birds and mammals caused by RNA viruses of the family Orthomyxoviridae, the influenza viruses. The virus is divided into three main types (Influenzavirus A, Influenzavirus B, and Influenzavirus C), which are distinguished by differences in two major internal proteins (hemagglutinin (HA) and neuraminidase (NA), which are the most important targets for the immune system. Hemagglutinin binds to the sialic acid-containing receptors on the surface of host cells during initial infection and at the end of an infectious cycle which makes it a great target for vaccine studies.