膜杰作
Star Staining
抗体来源（Source）
Monoclonal Anti-Human p-tau217 Antibody, Mouse IgG1 (6G7C8) is a Mouse monoclonal antibody recombinantly expressed from HEK293 cells.
克隆号（Clone）
6G7C8
种属（Species）
Mouse
亚型（Isotype）
Mouse IgG1 | Mouse Kappa
偶联（Conjugate）
Unconjugated
抗体类型（Antibody Type）
Recombinant Monoclonal
种属反应性（Reactivity）
Human
免疫原（Immunogen）
Recombinant polypeptide protein.
特异性（Specificity）
Specifically recognizes Human p-tau217 Protein.
应用（Application）
| Application | Recommended Usage |
| ELISA | 0.03-63 ng/mL |
纯度（Purity）
>95% as determined by SDS-PAGE.
>90% as determined by SEC-MALS.
纯化（Purification）
Protein A purified / Protein G purified
制剂（Formulation）
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
重构方法（Reconstitution）
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存储（Storage）
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
- -20°C to -70°C for 12 months in lyophilized state;
- -70°C for 3 months under sterile conditions after reconstitution.
电泳（SDS-PAGE）
Monoclonal Anti-Human p-tau217 Antibody, Mouse IgG1 (6G7C8) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95% (With Star Ribbon Pre-stained Protein Marker).
SEC-MALS
The purity of Monoclonal Anti-Human p-tau217 Antibody, Mouse IgG1 (6G7C8) (Cat. No. TAU-MY2102) is more than 90% and the molecular weight of this protein is around 130-160 kDa verified by SEC-MALS.
Report
活性（Bioactivity）-ELISA
Immobilized Recombinant Human p-Tau217 Protein at 1 μg/mL (100 μL/well) can bind Monoclonal Anti-Human p-tau217 Antibody, Mouse IgG1 (6G7C8) (Cat. No. TAU-MY2102) with a linear range of 0.03-2 ng/mL (QC tested).
Protocol
背景（Background）
Tau, the microtubule‐associated protein, forms insoluble filaments that accumulate as neurofibrillary tangles in Alzheimer's disease (AD) and related tauopathies. Under physiological conditions, tau regulates the assembly and maintenance of the structural stability of microtubules. In the diseased brain, however, tau becomes abnormally hyperphosphorylated, which ultimately causes the microtubules to disassemble, and the free tau molecules aggregate into paired helical filaments.
