应用(Application)
Flow Cytometry.
种属(Species)
Mouse
亚型(Isotype)
IgG1
特异性(Specificity)
This product is a specific antibody specifically reacts with human IL-4 protein.
免疫原(Immunogen)
Purified Human IL-4 Protein.
偶联(Conjugate)
PE
Excitation Wavelength: 488 nm / 561 nm
Emission Wavelength: 575 nm
制剂(Formulation)
Supplied as 0.2 μm filtered solution in PBS, pH7.4, 0.2% BSA, 0.03% Proclin300 with trehalose as protectant.
Contact us for customized product form or formulation.
存储(Storage)
Please protect from light and avoid repeated freeze-thaw cycles.
This product is stable after storage at:
- Store at 2° to 8°C.
- Do not use after the expiration date shown on the label.
质量管理控制体系(QMS)
背景(Background)
Interleukin-4, is a cytokine that induces differentiation of naive helper T cells (Th0 cells to Th2 cells). In the presence of IL-4 and IL-13, cytokines that are produced in a Th-2 type response, particularly during allergy and parasitic infections, macrophages become differentially activated, And this cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. Recently, researcher found that the cytokine IL-4 plays a key role in development of innate CD8+ T cells in the thymus of several gene-deficient mouse strains, including Itk, KLF2, CBP and Id3, without previous exposure to antigen.