申请GMP级别产品
试用装

Three independent lots of GMP Human IL-15 (Cat.No. GMP-L15H13) were tested for their ability to stimulate the proliferation of CTLL-2 cells. Average specific activity of GMP Human IL-15 was defined to be more than 0.8 x 107 IU/mg after calibration against human IL-15 WHO International Standards (NIBSC code: 95/554).

GMP IL-2
GMP IL-7
GMP IL-15
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Recombinant Human IL-7 and IL-15 premium and GMP grade proteins were evaluated under the same conditions for activity by measuring the ability to stimulate the proliferation of CTLL-2 cells. Performances were almost identical between both grades, enabling a seamless transition into clinicla research. Bioactivity Analysis by Cell-based Assays.

GMP IL-2
GMP IL-7
GMP IL-15
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Cell-based assays were performed on both liquid (pre-lyophilized) GMP proteins and lyophilized GMP proteins. GMP proteins were left outside for at most 72 hours (liquid) and 90 days (lyophilized) before evaluation. Liquid GMP proteins also underwent several freeze-thaw cycles to evaluate its stability in varying conditions. No difference in IL-15 activity was observed, showing extreme stability under non-ideal conditions.

GMP IL-2
GMP IL-7
GMP IL-15
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