IL-17 RA & IL-17 RC分子别名
IL-17 RA & IL-17 RC,IL-17RA & IL-17RC,CD217 & IL-17 RC
IL-17 RA & IL-17 RC分子背景
Also binds heterodimers formed by IL17A and IL17F as part of a heterodimeric complex with IL17RC. Cytokine binding triggers homotypic interaction of IL17RA and IL17RC chains with TRAF3IP2 adapter, leading to TRAF6-mediated activation of NF-kappa-B and MAPkinase pathways, ultimately resulting in transcriptional activation of cytokines, chemokines, antimicrobial peptides and matrix metalloproteinases, with potential strong immune inflammation.