LGR4 靶点蛋白|抗体药物|临床药物信息 - ACROBiosystems中国

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货号	物种	产品描述	蛋白结构	纯度	活性
LG4-H52H3	Human	Human LGR4 / GPR48 protein, His Tag

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LGR4分子别名

LGR4, GPR48, G-protein coupled receptor 48, Leucine-rich repeat-containing G-protein coupled receptor 4

LGR4分子背景

The fourth member of the leucine-rich repeat-containing GPCR family (LGR4, frequently referred to as GPR48) together with its family members LGR5 and -6, bind to R-spondins (RSPOs)-1–4 and result in Wnt signaling potentiation. In addition, LGR4 (as well as LGR5 and -6) is implicated in multiple cancers and promotes invasion and metastasis in colorectal, prostate, and cervical cancer cell lines.

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