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 > 【CD45】

CD45信息

英文名称：Leukocyte common antigen
中文名称：白细胞共同抗原
靶点别称：PTPRC，T200，CD45，Protein Tyrosine Phosphatase， Receptor Type C，CD45 Antigen，L-CA，Protein Tyrosine Phosphatase， Receptor Type， C Polypeptide，Receptor-Type Tyrosine-Protein Phosphatase C，T200 Leukocyte Common Antigen，Leukocyte Common Antigen，T200 Glycoprotein，EC 3.1.3.48，CD45R，GP180，B220，LCA，LY5，Leukocyte Common Antigens，Protein Tyrosine Phosphatase Receptor Type C，EC:3.1.3.48
上市药物数量：0
临床药物数量：3
最高研发阶段：临床三期

CD45产品列表

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货号 物种 产品描述 蛋白结构 纯度 活性
CD5-H5259
Human		 Human CD45 / PTPRC Protein, Llama IgG2b Fc Tag, low endotoxin
CD5-H52H8
Human		 Human CD45 / PTPRC protein, His Tag
CD5-H82E7
Human		 Biotinylated Human CD45 / PTPRC protein, His,Avitag™ (MALS verified)
CD5-H82E8
Human		 Biotinylated Human CD45 / PTPRC Protein, His,Avitag™
ACRO质量管理体系
 
评论(2)
CD5-H82E7|Biotinylated Human CD45 / PTPRC protein, His,Avitag™ (MALS verified)
  1. +49XXXXXXX4732
    2. 3人赞
  2. Dear Sir or Madam, I had an overall good service from Acro Biosystems. Shipment was fast and product quality was good. Got the protocol for QC after asking the customer service. Protocol for QC was easy to understand and repeat. Easy way to download the Certificate of Analysis via the printed QR code on product vials. Customer service answered very fast and was very friendly. QC of biotinylated human CD45 protein vs. Human Galectin-1 protein (GA1-H4113) was fine. Biotinylated human CD45 protein worked fine and could be loaded on Streptavidin biosensors (Octet system).
  3. >
  4. 2022-01-01
CD5-H5259|Human CD45 / PTPRC Protein, Llama IgG2b Fc Tag, low endotoxin
  1. 130XXXXXXX2
    2. 1人赞
  2. Human CD155蛋白与TIGIT蛋白的结合是现在靶向药物研究的热点，该产品用于靶向TIGIT抗体的竞争ELISA方法开发中重复性好，分装保存性质稳定，重现性好，质量比较可靠！
  3. 2023-01-31
 

CD45分子别名

CD45,PTPRC,L-CA,T200

CD45分子背景

CD45 is a receptor protein tyrosine phosphatase, also known as Ly-5 or leukocyte common antigen. CD45 mainly involves in the initiation of T cell receptor signaling by controlling the activation of the Src family protein-tyrosine kinases Lck and Fyn. CD45 deficiency causes in T- and B-lymphocyte dysfunction in the form of severe combined immune deficiency. It also takes a significant role in autoimmune diseases and cancer as well as in infectious diseases including fungal infections.

CD45临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
I-131-Apamistamab BC8-I-131; BC-8; 131IBC8 临床三期 弗莱德哈钦森癌症研究中心 眼内淋巴瘤, Sezary综合征, 铁粒幼细胞性贫血, 急性髓细胞样白血病, T-细胞淋巴瘤, 间变大细胞淋巴瘤, 皮肤T细胞淋巴瘤, 性腺组织肿瘤, 华氏巨球蛋白血症, 急性淋巴细胞白血病, 淋巴瘤, Burkitt淋巴瘤, 非霍奇金淋巴瘤, 蕈样真菌病, 慢性淋巴细胞白血病, T-细胞白血病, 大颗粒淋巴细胞白血病, 慢性骨髓单核细胞性白血病, 白血病, 造血干细胞移植, 外周T细胞淋巴瘤, B-细胞淋巴瘤, 边缘带B细胞淋巴瘤, 难治性贫血伴原始细胞过多, 毛细胞白血病, 骨髓增生异常综合征, 循环肿瘤细胞, 淋巴瘤样肉芽肿病, 弥漫性大B-细胞淋巴瘤, 淋巴瘤，大细胞，免疫母细胞, 霍奇金病, 全血细胞减少, 滤泡性淋巴瘤, 套细胞淋巴瘤 详情
Immunomodulatory progenitor cell therapy (Celixir) 临床三期 Celixir 心内膜心肌纤维化, 心肌疾病 详情
At 211 MAb BC8-B10 临床二期 弗莱德哈钦森癌症研究中心 肿瘤 详情

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