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 > 【PTK7】

PTK7信息

英文名称：Protein-tyrosine kinase 7
中文名称：蛋白酪氨酸激酶-7
靶点别称：Colon carcinoma kinase 4，Inactive tyrosine-protein kinase 7，Tyrosine-protein kinase-like 7，CCK-4，PTK7，Protein Tyrosine Kinase 7 (Inactive)，Pseudo Tyrosine Kinase Receptor 7，PTK7 Protein Tyrosine Kinase 7，CCK4，Protein-Tyrosine Kinase 7，Protein Tyrosine Kinase 7
上市药物数量：0
临床药物数量：2
最高研发阶段：临床二期

PTK7产品列表

筛选结果
产品库
物种
标签
属性
标记
货号 物种 产品描述 蛋白结构 纯度 活性
PT7-H52H3
Human		 Human PTK7 / CCK4 Protein, His Tag (MALS verified)
PT7-C52H3
Cynomolgus / Rhesus macaque		 Cynomolgus / Rhesus macaque PTK7 / CCK4 Protein, His Tag (MALS verified)
PT7-M52H3
Mouse		 Mouse PTK7 / CCK4 Protein, His Tag (MALS verified)
CHEK-ATP186
Human		 HEK293/Human PTK7 Stable Cell Line
PT7-H5253
Human		 Human PTK7 / CCK4 Protein, Fc Tag (MALS verified)
PT7-H82E5
Human		 Biotinylated Human PTK7 / CCK4 protein, His,Avitag™ (MALS verified)
PT7-H82F5
Human		 Biotinylated Human PTK7 / CCK4 protein, Fc,Avitag™ (MALS verified)
PT7-M5256
Mouse		 Mouse PTK7 / CCK4 Protein, Fc Tag (MALS verified)
PT7-R5255
Rat		 Rat PTK7 / CCK4 Protein, Fc Tag
PT7-R52H4
Rabbit		 Rabbit PTK7 / CCK4 Protein, His Tag (MALS verified)
PT7-R52H6
Rat		 Rat PTK7 / CCK4 Protein, His Tag (MALS verified)
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评论(23)
PT7-H5253|Human PTK7 / CCK4 Protein, Fc Tag (MALS verified)
  1. 153XXXXXXX9
    2. 1人赞
  2. 此蛋白亲和力特别好，而且比较稳定，在推荐的条件下进行溶解处理，使用时不同批次之间差异很小，在ELISA实验中，不管是用于包被还是标准品都有很好的重现性，后续还会继续使用，而且也会尝试其他蛋白。protocal也很详细，还有赠品，物流也快。
  3. >
  4. 2021-08-23
PT7-C52H3|Cynomolgus / Rhesus macaque PTK7 / CCK4 Protein, His Tag (MALS verified)
  1. 182XXXXXXX4
    2. 1人赞
  2. ACRO的产品一如既往的高品质，无论是在PK，BA，还有流式实验都变现出良好的性能，随带的COA写的十分详细对使用帮助很大。
  3. 2023-04-25
PT7-H52H3|Human PTK7 / CCK4 Protein, His Tag (MALS verified)
  1. 183XXXXXXX6
    2. 0人赞
  2. 经SPR验证，测单价亲和力，抗人FC芯片，load稀释后抗体，加入稀释后的PTK7,His tag，亲和力常数为4 nM。
  3. >
  4. 2022-07-21
查看更多评论
 

PTK7分子别名

PTK7,CCK4,CCK-4,Tyrosine-protein kinase-like 7,Protein-tyrosine kinase 7,Protein-tyrosine kinase 7

PTK7分子背景

PTK7, highly expressed in lung, liver, pancreas, kidney, placenta and melanocytes. Weakly expressed in thyroid gland, ovary, brain, heart and skeletal muscle. Also expressed in erythroleukemia cells. Inactive tyrosine kinase involved in Wnt signaling pathway. Component of both the non-canonical (also known as the Wnt/planar cell polarity signaling) and the canonical Wnt signaling pathway. Functions in cell adhesion, cell migration, cell polarity, proliferation, actin cytoskeleton reorganization and apoptosis. Has a role in embryogenesis, epithelial tissue organization and angiogenesis.

PTK7临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
PRO-1107 PRO-1107 临床二期 普方生物制药（苏州）有限公司 实体瘤, 卵巢癌, 胃癌, 食道癌, 三阴性乳腺癌, 尿路上皮癌, 子宫内膜癌, 非小细胞肺癌 详情
Cofetuzumab Pelidotin PF-06647020; PF-6647020; PTK7-ADC; PF-06523435; PF-7020; hu-24; ABBV-647; Anti-PTK7 ADC; h6M24-vc0101 临床一期 艾伯维, Stemcentrx Inc 肿瘤, 非小细胞肺癌 详情

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