Recombinant Proteins iso9001 ISO13485
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 > 【KREMEN2】重组蛋白信息

KREMEN2产品列表

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货号 物种 产品描述 蛋白结构 纯度 活性
KR2-H52H3
Human
Human Kremen-2 protein, His Tag
 
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KREMEN2 Molecule Synonym Name

KREMEN2, Kremen-2, KRM2, Dickkopf receptor 2,Kringle domain-containing transmembrane protein 2

KREMEN2 分子背景

Kremen2 (Krm2) plays an important role in embryonic development, bone formation, and tumorigenesis as a crucial regulator of classical Wnt/β-catenin signaling pathway. Krm1 and its paralog Krm2 share the ability to bind Dkk1 and inhibit Wnt signaling, both processes previously shown to rely on the extracellular domain. Previous studies have shown that Krm2 may be involved in embryonic development, bone formation, neural ridge formation and tumorigenesis and could be a biomarker of grading and a potential therapeutic target in gastric cancer.

KREMEN2 参考文献

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