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 > 【FGF19】

FGF19信息

英文名称:Fibroblast growth factor 19
中文名称:成纤维细胞因子19
靶点别称:FGF-19
上市药物数量:0
临床药物数量:1
最高研发阶段:临床二期

FGF19产品列表

产品库
物种
属性
货号 物种 产品描述 蛋白结构 纯度 活性
FG9-H51H3
Human
Human FGF19 Protein, His Tag
FG9-H5253
Human
Human FGF19 Protein, Fc Tag
ACRO质量管理体系
 
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FGF19分子别名

FGF19,FGF-19,Fibroblast growth factor 19

FGF19分子背景

Fibroblast growth factor (FGF)19 is the first members of a new subfamily of FGFs and could act as hormones. During fetal life, FGF15/19 is involved in organogenesis, affecting the development of the ear, eye, heart, and brain. FGFs–FGFRs are involved in regulation of many biological processes such as embryonic development, cell proliferation, differentiation, and tissue repair. The dysregulation of FGF–FGFR was observed in different types of diseases, disorders, and cancers. Notably, aberrant expression of FGF19/FGFR4 contributes to Hepatocellular Carcinoma progression.

FGF19临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
Aldafermin NGM-282; M70; M-70; NGM282 临床二期 Ngm Biopharmaceuticals Inc 胆汁性肝硬化, 便秘, 肠易激综合征, 非酒精性脂肪性肝炎, 肾功能不全, 胆汁酸吸收障碍, 纤维化, 原发性硬化性胆管炎, 腹泻, 肝功能衰退, 吸收不良综合征, 糖尿病 详情

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