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 > 【DNase I】

DNase I信息

英文名称:Deoxyribonuclease 1
中文名称:脱氧核糖核酸酶1
靶点别称:EC:3.1.21.1,Deoxyribonuclease I,Dornase alfa,DNase I, Lysosomal,DNase I,DNL1,DNASE1,Deoxyribonuclease 1,DRNI,Human Urine Deoxyribonuclease I,Deoxyribonuclease-1,EC 3.1.21.1
上市药物数量:1
临床药物数量:0
最高研发阶段:批准上市

DNase I产品列表

产品库
物种
属性
货号 物种 产品描述 蛋白结构 纯度 活性
ASE-A002
Bovine
resDetect™ DNase Activity Assay Kit (Fluorescence)
ACRO质量管理体系
 
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DNase I分子别名

DNase I,Deoxyribonuclease-1,Deoxyribonuclease I

DNase I分子背景

Serum endocuclease secreted into body fluids by a wide variety of exocrine and endocrine organs. Expressed by non-hematopoietic tissues and preferentially cleaves protein-free DNA (By similarity). Among other functions, seems to be involved in cell death by apoptosis. Binds specifically to G-actin and blocks actin polymerization. Together with DNASE1L3, plays a key role in degrading neutrophil extracellular traps (NETs) (By similarity). NETs are mainly composed of DNA fibers and are released by neutrophils to bind pathogens during inflammation (By similarity).

DNase I上市药物信息

英文名称 中文名称 研发代码 研发阶段 公司 最早商品名 最早批准国家 最早适应症 最早批准公司 最早批准日期 适应症 临床试验
Chorionic Gonadotropin LDI-200 批准上市 Angiogene Pharmaceuticals 前列腺癌, 急性髓细胞样白血病, 女性不育, 性腺功能减退症, 隐睾 详情

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