BTN2A1分子别名
BK14H9.1,BT2.1,BTF1,BTF1BT2.1butyrophilin BTF1,BTN2A1,butyrophilin subfamily 2 member A1,butyrophilin,subfamily 2,member A1,DJ3E1.1,FLJ36567
BTN2A1分子背景
Duplication events have led to three paralogues of BTN2A in primates: BTN2A1, BTN2A2, and BTN2A3. In humans, only BTN2A1 has been functionally characterised; it has been detected on epithelial cells and leukocytes, and identified as a novel ligand of dendritic cell-specific ICAM-3 grabbing nonintegrin (DCSIGN), a C-type lectin receptor that acts as an internalization receptor for HIV-1, HCV, and other pathogens. BTN2A2 mRNA has been shown to be expressed in circulating human immune cells.