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 > 【Thrombopoietin】

Thrombopoietin信息

英文名称：Thrombopoietin
中文名称：血小板生成素
靶点别称：Prepro-Thrombopoietin，MPL Ligand，MGDF，THCYT1，MKCSF，MPLLG，TPO，Thrombopoietin，THPO，Megakaryocyte colony-stimulating factor，Megakaryocyte growth and development factor，C-mpl ligand，ML，Myeloproliferative Leukemia Virus Oncogene Ligand，Megakaryocyte Stimulating Factor，Thrombopoietin Nirs Variant 1
上市药物数量：0
临床药物数量：0
最高研发阶段：终止

Thrombopoietin产品列表

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货号 物种 产品描述 蛋白结构 纯度 活性
GMP-THNH25
Human		 GMP Human Thrombopoietin Protein
THN-H5214
Human		 Human Thrombopoietin / TPO Protein, Tag Free
THN-H5216
Human		 Human Thrombopoietin / TPO Protein, premium grade
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Thrombopoietin分子别名

THPO,MGC163194,MGDF,MKCSF,ML,MPLLG,TPO,THCYT1

Thrombopoietin分子背景

Thrombopoietin (TPO) is a 332 amino acid glycoprotein made primarily in the liver and act as the major physiological regulator of platelet production. TPO binds the TPO receptor, activates JAK and STAT pathways, thus stimulating megakaryocyte growth and platelet production. Additionally, further investigation uncovered that thrombopoietin is a critical cytokine promoting hematopoietic rebound after myeloablation and its transcripts are expressed by multiple cellular sources.

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