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UBE1信息

英文名称:Ubiquitin-like modifier-activating enzyme 1
中文名称:泛素样修饰物活化酶-1
靶点别称:EC:6.2.1.45,UBE1,Ubiquitin-Activating Enzyme E1 (A1S9T And BN75 Temperature Sensitivity Complementing),UBA1, Ubiquitin-Activating Enzyme E1 Homolog (Yeast),POC20 Centriolar Protein Homolog (Chlamydomonas),Ubiquitin-Like Modifier Activating Enzyme 1,Testicular Secretory Protein Li 63,EC 6.2.1.45,CFAP124,AMCX1,POC20,SMAX2,UBA1A,UBE1X,A1S9,A1ST,GXP1,Ubiquitin-activating enzyme E1,Protein A1S9,A1S9T,Ubiquitin-like modifier-activating enzyme 1,UBA1,Ubiquitin Like Modifier Activating Enzyme 1,A1S9T An
上市药物数量:0
临床药物数量:1
最高研发阶段:临床一期

UBE1产品列表

产品库
物种
标签
属性
货号 物种 产品描述 蛋白结构 纯度 活性
UB1-H5248
Human
Human UBE1 / UBA1 Protein, His Tag
ACRO质量管理体系
 
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UBE1分子别名

A1S9T and BN75 temperature sensitivity complementing,A1S9T,A1ST,AMCX1,GXP1,MGC4781,POC20 centriolar protein homolog,POC20,Protein A1S9,SMAX2,UBA1,UBA1, ubiquitin-activating enzyme E1 homolog A,UBA1A,UBE1,UBE1A1S9,UBE1X,ubiquitin-activating enzyme E1 (A1S9T and BN75 temperature sensitivitycomplementing),Ubiquitin-activating enzyme E1,Ubiquitinactivating Enzyme,Ubiquitin-activating Enzyme,ubiquitin-like modifier activating enzyme 1,ubiquitin-like modifier-activating enzyme 1

UBE1分子背景

The protein encoded by this gene catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation. This gene complements an X-linked mouse temperature-sensitive defect in DNA synthesis, and thus may function in DNA repair. It is part of a gene cluster on chromosome Xp11.23. Alternatively spliced transcript variants that encode the same protein have been described. [provided by RefSeq, Jul 2008]

UBE1临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
TAK-243 TAK-243; MLN-7243 临床一期 Takeda Pharmaceutical Co Ltd 实体瘤, 慢性骨髓单核细胞性白血病, 骨髓增生异常综合征, 急性髓细胞样白血病, 淋巴瘤 详情

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