AGR2分子别名
Anterior gradient protein 2 homolog,AG-2,hAG-2,HPC8,Secreted cement gland protein XAG-2 homolog,AGR2
AGR2分子背景
Anterior gradient 2 (AGR2) is a normal endoplasmic reticulum protein that has two important abnormal functions, amphibian limb regeneration and human cancer metastasis promotion. These normal intracellular and abnormal extracellular roles can be attributed to the multidomain structure of AGR2. The NMR structure shows that AGR2 consists of an unstructured N-terminal region followed by a thioredoxin fold.