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CD79A信息

英文名称:B-cell antigen receptor complex-associated protein alpha chain
中文名称:B细胞抗原受体复合体相关蛋白α链
靶点别称:Ig-alpha,MB-1 membrane glycoprotein,Membrane-bound immunoglobulin-associated protein,Surface IgM-associated protein
上市药物数量:0
临床药物数量:1
最高研发阶段:临床二期

CD79A产品列表

货号 物种 产品描述 蛋白结构 纯度 活性
CDA-C52H3
Cynomolgus
Cynomolgus CD79A Protein, His Tag
CDA-H52H8
Human
Human CD79A Protein, His Tag
ACRO质量管理体系
 
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CD79A 分子别名

CD79A, CD79a, B-cell antigen receptor complex-associated protein alpha chain, B-cell antigen receptor complex-associated protein alpha chain, Ig-alpha, MB-1 membrane glycoprotein, Membrane-bound immunoglobulin-associated protein, Surface IgM-associated p

CD79A 分子背景

B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain(CD79a), also known as CD79α, IgM-α, Ig-α and mb-1, which is a signaling component of the preB cell receptor (preBCR). Covalently linked CD79a and CD79b heterodimer constitutes the B cell antigen receptor (BCR) with membrane immunoglobulin (mIg) in a non-covalent association. CD79a is required in cooperation with CD79b for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR), leading to internalization of the complex, trafficking to late endosomes and antigen presentation. CD79a is also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells.

CD79A 前沿进展

CD79A临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
bbT-369 bbT-369 临床二期 Bluebird Bio Inc 弥漫性大B-细胞淋巴瘤, 非霍奇金淋巴瘤 详情

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