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CCL2信息

英文名称:C-C motif chemokine 2
中文名称:C-C基序趋化因子-2
靶点别称:MCP1,HC11,Monocyte chemotactic protein 1,Monocyte chemoattractant protein 1,CCL2,C-C Motif Chemokine Ligand 2,Monocyte Chemotactic And Activating Factor,Monocyte Secretory Protein JE,Small Inducible Cytokine A2 (Monocyte Chemotactic Protein 1, Homologous To Mouse Sig-Je),Small Inducible Cytokine Subfamily A (Cys-Cys), Member 2,Monocyte Chemoattractant Protein-1,Chemokine (C-C Motif) Ligand 2,Small-Inducible Cytokine A2,SCYA2,MCP-1,MCAF,Monocyte Chemotactic Protein 1, Homologous To Mouse Sig-Je,C
上市药物数量:0
临床药物数量:2
最高研发阶段:临床二期

CCL2产品列表

产品库
物种
标签
货号 物种 产品描述 蛋白结构 纯度 活性
CC2-H5255
Human
Human CCL2 / MCP-1 Protein, Fc Tag (MALS verified)
CEA-B036
Human
ClinMax™ Human MCP-1 / CCL2 ELISA Kit
ACRO质量管理体系
 
评论(2)
CEA-B036|ClinMax™ Human MCP-1 / CCL2 ELISA Kit
  1. 176XXXXXXX8
  2. 0人赞
  3. 第一次用Acro家的ELISA检测试剂盒,一直以来蛋白用的比较多。试剂盒检测灵敏、操作方便,可以满足试验要求,会面需要还会继续关注。
  4. 2024-10-08
CC2-H5255|Human CCL2 / MCP-1 Protein, Fc Tag (MALS verified)
  1. 183XXXXXXX0
  2. 0人赞
  3. 应用于诱导巨噬细胞的迁移,希望可以进行再小包装的分装或者是配备相应的稀释缓冲液,对于实验来说还是很管用滴!
  4. 2023-05-17
 

CCL2分子别名

CCL2,C-C motif chemokine 2,MCP-1,MCAF

CCL2分子背景

Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. CCL2, a member of the CC subfamily, is characterized by two adjacent cysteine residues. CCL2 displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. Elevated expression of the encoded protein is associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

CCL2临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
AFX-5931 AFX-5931 临床二期 湿疹 详情
64CU-DOTA-ECL1i 临床一期 华盛顿大学医学院 颈动脉疾病, 心脏病, 动脉硬化 详情

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