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KIR3DL3信息

英文名称:Killer cell immunoglobulin-like receptor 3DL3
中文名称:杀伤细胞免疫球蛋白样受体3DL3
靶点别称:CD158 antigen-like family member Z,Killer cell inhibitory receptor 1,CD158z,KIRC1
上市药物数量:0
临床药物数量:1
最高研发阶段:临床一期

KIR3DL3产品列表

ACRO质量管理体系
 
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KIR3DL3分子别名

Killer cell immunoglobulin-like receptor 3DL3,CD158 antigen-like family member Z,Killer cell inhibitory receptor 1,CD158z,KIR3DL3,KIR3DL7,KIRC1

KIR3DL3分子背景

the inhibitory KIR surface receptors possessing three extracellular immunoglobin (Ig) domains (3D) and only one inhibitory motif within the long cytoplasmic domain (L) due to a premature stop codon. Moreover, exon 6 of KIR3DL3 encoding the stem part of the receptor is also absent, which differs from other inhibitory KIRs. Understanding the function of KIR3DL3 is further complicated by the unknown identity of the specific ligand, but its importance is highlighted by its presence in all human KIR haplotypes with
120 distinct polymorphic alleles of the coding sequence [

KIR3DL3临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
NPX-267 NPX-267 临床一期 NextPoint Therapeutics Inc 肿瘤 详情

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