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 > 【Cadherin-17】

Cadherin-17信息

英文名称：Cadherin-17
中文名称：钙粘蛋白17
靶点别称：Liver-intestine cadherin，HPT-1，Intestinal peptide-associated transporter HPT-1，LI-cadherin，HPT-1 Cadherin，Cadherin 17， LI Cadherin (Liver-Intestine)，HPT1，Human Intestinal Peptide-Associated Transporter HPT-1，LI Cadherin，Cadherin，Cadherin 17，Human Peptide Transporter 1
上市药物数量：0
临床药物数量：3
最高研发阶段：临床二期

抗体项目交易平台

项目名称 项目阶段 分子类型 分子来源 疾病领域 适应症
CDH17 mAb - 03 PCC 单抗 鼠源人源化 实体瘤 胃癌,胰腺癌,结直肠癌

Cadherin-17产品列表

筛选结果
产品库
物种
标签
属性
标记
货号 物种 产品描述 蛋白结构 纯度 活性
CA7-H52H3
Human		 Human Cadherin-17 / CDH17 Protein, His Tag
CA7-H52E6
Human		 Biotinylated Human Cadherin-17 / CDH17 Protein, His,Avitag™ (MALS verified)
CA7-M52H5
Mouse		 Mouse Cadherin-17 / CDH17 Protein, His Tag (MALS verified)
CA7-C5253
Cynomolgus		 Cynomolgus Cadherin-17 / CDH17 Protein, Fc Tag (MALS verified)
CA7-C52H3
Cynomolgus		 Cynomolgus Cadherin-17 / CDH17 Protein, His Tag (MALS verified)
CA7-C82E8
Cynomolgus		 Biotinylated Cynomolgus Cadherin-17 / CDH17 Protein, His,Avitag™ (MALS verified)
CA7-H5258
Human		 Human Cadherin-17 / CDH17 Protein, Fc Tag (MALS verified)
CA7-H52A9
Human		 Human Cadherin-17 / CDH17 Protein, Mouse IgG1 Fc Tag
CA7-H82F9
Human		 Biotinylated Human Cadherin-17 / CDH17 Protein, Fc,Avitag™ (MALS verified)
CA7-M5256
Mouse		 Mouse Cadherin-17 / CDH17 Protein, Fc Tag (MALS verified)
CA7-M82E7
Mouse		 Biotinylated Mouse Cadherin-17 / CDH17 Protein, His,Avitag™ (MALS verified)
CA7-M82F3
Mouse		 Biotinylated Mouse Cadherin-17 / CDH17 Protein, Fc,Avitag™ (MALS verified)
CA7-R52H3
Rat		 Rat Cadherin-17 / CDH17 Protein, His Tag (MALS verified)
CHEK-ATP173
Human		 HEK293/Human Cadherin-17 Stable Cell Line
ACRO质量管理体系
 
评论(29)
CA7-H52E6|Biotinylated Human Cadherin-17 / CDH17 Protein, His,Avitag™ (MALS verified)
  1. 135XXXXXXX6
    2. 3人赞
  2. 购买生物素标记的CDH17蛋白用于Elisa实验和SPR实验，蛋白经过了MALS验证，符合实验的需求。该蛋白纯度高，稳定性好，生物素标记率高，后续会持续购买。
  3. 2022-11-30
CA7-H52H3|Human Cadherin-17 / CDH17 Protein, His Tag
  1. 182XXXXXXX6
    2. 2人赞
  2. 购买cadherin17靶点抗原重组蛋白，主要用于相关单克隆抗体亲和力检测，与同行产品相比活性较高，不同批次间产品质量统一性好，性价比高，值得推荐！
  3. >
  4. 2023-02-11
CA7-H5258|Human Cadherin-17 / CDH17 Protein, Fc Tag (MALS verified)
  1. 188XXXXXXX4
    2. 1人赞
  2. 产品非常可靠，使用方便简洁，效果稳定可靠，结果重现良好，而且产品储存起来非常稳定，在放置了半年后依然可以使用，实验结果挺好的，非常可靠稳定，对实验帮助很大，下次还会购买！
  3. 2023-07-04
查看更多评论
 

Cadherin-17分子别名

Cadherin-17,CDH17,HPT-1,LI-cadherin

Cadherin-17分子背景

Cadherin-17, also known as liver-intestine (LI) Cadherin, belongs to the cadherin family of calcium-dependent cell adhesion molecules. In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.

Cadherin-17临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
CHM-2101 CDH17-CAR T; CHM-2101; CHM2101; CHM-2101 CAR-T cells 临床二期 宾夕法尼亚大学 胃癌, 胰腺癌, 神经内分泌瘤, 结直肠癌, 胃肠道癌症 详情
BI-905711 BI-905711 临床一期 Boehringer Ingelheim Gmbh 胰腺癌, 胆管上皮癌, 胃肠道癌症 详情
ARB-202 ARB-202 临床一期 Arbele Corp 肝癌, 胆管癌, 胃癌, 胰腺癌, 胆管上皮癌, 结直肠癌, 食道腺癌, 胃肠道癌症 详情

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