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CD131产品列表

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货号 物种 产品描述 蛋白结构 纯度 活性
CD1-H5256
Human
Human IL-3 R Beta / CD131 Protein, Fc Tag (MALS verified)
ACRO质量管理体系
 
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CD131分子别名

IL-3 R Beta,CD131,Common beta Chain

CD131分子背景

CD131- the common β Subunit, is a member of the type 1 cytokine
receptor family. There are three major classes of heteroreceptor complexes, where the receptor complex utilises a common shared receptor subunit as a signal-transducing chain along with a cytokine specific subunit. These three classes include those which use gp130, those which use γc and those which use the common β subunit, βc(CD131). CD131 is shared by three of the “four-helical bundle” family of cytokines; IL-3, IL-5 and GM-CSF, and forms a receptor complex along with a cytokine specific α chain for each of these cytokines.Moreover, even though each of these cytokines have their own specific α subunit, the co-utilisation of CD131 suggests a common intra-cellular process of both unique and/or overlapping activities on expressing cells.

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