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IGFBP-3 R产品列表

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货号 物种 产品描述 蛋白结构 纯度 活性
IGR-H5259
Human
Human IGFBP-3 R / TMEM219 Protein, Fc Tag (MALS verified)
ACRO质量管理体系
 
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IGFBP-3 R分子别名

IGFBP-3 R,TMEM219,Insulin-like growth factor-binding protein 3 receptor,Transmembrane protein 219

IGFBP-3 R分子背景

IGFBP-3 R, also know as TMEM219, is a cell death receptor specific for IGFBP3. IGFBP-3R is expressed on the cell surface, interacts specifically with IGFBP-3 but not other IGFBP species. It activates initiator caspase-8, and mediates IGFBP-3-induced apoptosis in vitro and tumor suppression in vivo.

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