登录 | 注册    关注公众号  
微信公众号
搜索
 > 【Cadherin-6】

Cadherin-6信息

英文名称:Cadherin-6
中文名称:钙粘蛋白6
靶点别称:Kidney cadherin,K-cadherin,Cadherin 6, Type 2, K-Cadherin (Fetal Kidney),K-Cadherin,Cadherin-6,Kidney Cadherin,CAD6,KCAD
上市药物数量:0
临床药物数量:2
最高研发阶段:临床三期

抗体项目交易平台

项目名称 项目阶段 分子类型 分子来源 疾病领域 适应症
CDH6 mAb - 01 PCC 单抗 鼠源人源化 实体瘤 卵巢癌,肾细胞癌

Cadherin-6产品列表

ACRO质量管理体系
 
评论(2)
CA6-H5229|Human Cadherin-6 / KCAD / CDH6 Protein, His Tag
  1. 183XXXXXXX6
  2. 3人赞
  3. 经SPR验证,测单价亲和力,抗人FC芯片,load稀释后抗体,加入稀释后的CDH6,His tag,亲和力常数为4.72 nM。
  4. >
  5. 2022-07-21
CA6-M52H8|Mouse Cadherin-6 / KCAD / CDH6 Protein, His Tag
  1. 183XXXXXXX6
  2. 1人赞
  3. Human CDH6 与Mouse CDH6 的序列同源性高达99%, 为了验证我们筛选到的CDH6抗体与mouse CDH6是否有cross, 特地购买mouse CDH6抗原,ELISA检测抗体抗原结合情况。
  4. >
  5. 2023-02-14
 

Cadherin-6分子别名

CDH6,CAD6,KCAD,K-cadherin,Cadherin-6

Cadherin-6分子背景

Cadherin-6 (CDH6) is also known as Kidney cadherin (K-cadherin or KCAD), is a a type II classical cadherin from the cadherin superfamily. Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH6 / KCAD contains five cadherin domains. CDH6 is highly expressed in brain, cerebellum, and kidney. Lung, pancreas, and gastric mucosa show a weak expression and also expressed in certain liver and kidney carcinomas.

Cadherin-6临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
Raludotatug deruxtecan DS-6000a; DS6000a; DS-6000; R-DXd 临床三期 第一三共株式会社 卵巢癌, 实体瘤, 肾细胞癌, 腹膜癌, 输卵管癌 详情
AMT-707 AMT-707; CUSP-06 临床一期 普众发现医药科技有限公司 实体瘤, 卵巢癌, 肾细胞癌, 胆管上皮癌 详情

消息提示

请输入您的联系方式,再点击提交!

确定