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Claudin-1信息

英文名称:Claudin 1
中文名称:Claudin 1
靶点别称:Claudin-1,SEMP1,ILVASC,CLD1,Senescence-Associated Epithelial Membrane Protein 1,CLDN1
上市药物数量:0
临床药物数量:3
最高研发阶段:临床二期

Claudin-1产品列表

ACRO质量管理体系
 
评论(1)
CL1-H52P6|Human Claudin-1 Full Length Protein (VLP)
  1. 156XXXXXXX8
  2. 0人赞
  3. 用于检测抗体的结合特异性,使用贵公司CLAUDIN-6-VLP免疫获得的抗体,能够特异性结合CLAUDIN-6,但是不与该蛋白CLAUDIN-1-VLP交叉,效果很好。
  4. 2024-03-15
 

Claudin-1分子别名

CLD1, ILVASC, SEMP1

Claudin-1分子背景

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome. [provided by RefSeq, Jul 2008]

Claudin-1临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
ALE-C04 ALE-C04; ALE.C04 临床二期 Inserm 头颈癌, 肝癌, 头颈部鳞状细胞癌, 胆管上皮癌 详情
ALE-P02 ALE-P02; ALE.P02 临床二期 Alentis Therapeutics AG 实体瘤, 头颈部鳞状细胞癌, 食管鳞状细胞癌, 鳞状细胞癌, 非小细胞肺癌, 宫颈癌 详情
Lixudebart ALE-F02; ALE-F-02 临床二期 Alentis Therapeutics AG 肝硬化, 肾脏纤维化, 肾小球肾炎 详情

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