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CCR6信息

英文名称:C-C chemokine receptor type 6
中文名称
靶点别称:GPRCY4,STRL22,LARC receptor,CD196,CC-CKR-6,DRY6,GPR-CY4,CKR-L3,CCR-6,G-protein coupled receptor 29,Chemokine receptor-like 3,DCR2,CKRL3,G Protein-Coupled Receptor 29,Seven-Transmembrane Receptor, Lymphocyte, 22,DRY-6,CMKBR6,CD196 Antigen,Chemokine (C-C) Receptor 6,GPR29,C-C Motif Chemokine Receptor 6,BN-1,Chemokine (C-C Motif) Receptor 6,C-C CKR-6
上市药物数量:0
临床药物数量:3
最高研发阶段:临床二期

CCR6产品列表

产品库
物种
属性
货号 物种 产品描述 蛋白结构 纯度 活性
CC6-H52P3
Human
Human CCR6 Full Length Protein (VLP)
ACRO质量管理体系
 
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CCR6分子别名

BN-1, C-C CKR-6, CC-CKR-6, CCR-6, CD196, CKR-L3, CKRL3, CMKBR6, DCR2, DRY6, GPR29, GPRCY4, STRL22

CCR6分子背景

This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene.

CCR6临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
CCX-587 CCX-587 临床二期 Chemocentryx 银屑病 详情
IDOR-1117-2520 IDOR-11172520; IDOR-1117-2520 临床一期 Idorsia Pharmaceuticals Ltd 免疫紊乱 详情
PF-07054894 PF-07054894 临床一期 辉瑞 溃疡性结肠炎 详情

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